SCHEMBL68931

SCHEMBL68931

COC(=O)c1ccc(-c2cccc(C(=O)OC)c2)cc1

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.69
CA9 Q16790 2/20 0.69
CA1 P00915 1/20 0.69
CA2 P00918 1/20 0.69
PLAU P00749 7/20 0.67
EGFR P00533 1/20 0.64
ERN1 O75460 2/20 0.63
FNTA P49354 1/20 0.60
FNTB P49356 1/20 0.60
PGGT1B P53609 1/20 0.60
PLAT P00750 2/20 0.59
PLG P00747 1/20 0.59
TSHR P16473 1/20 0.59
PTPN1 P18031 1/20 0.57
GABRG2 P18507 1/20 0.56
GABRB3 P28472 1/20 0.56
GABRA5 P31644 1/20 0.56
GABRA3 P34903 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27715902 0.94 CA12 (0.71) CA12CA9CA1CA2PLAU
SCHEMBL28189889 0.92 EGFR (0.68) CA12CA9CA1CA2PLAU
SCHEMBL67941 0.92 CA12 (0.68) CA12CA9CA1CA2PLAU
SCHEMBL4433239 0.91 CA12 (0.60) CA12CA9CA1CA2PLAU
SCHEMBL7224347 0.91 CA12 (0.64) CA12CA9CA1CA2PLAU
SCHEMBL5944327 0.91 EGFR (0.63) CA12CA9CA1CA2PLAU
SCHEMBL1221576 0.91 TSHR (0.67) CA12CA9CA1CA2PLAU
SCHEMBL29410906 0.91 TSHR (0.67) CA12CA9CA1CA2PLAU
SCHEMBL27589486 0.90 TSHR (0.64) CA12CA9CA1CA2PLAU
SCHEMBL1661764 0.89 CA12 (0.66) CA12CA9CA1CA2PLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8859690-B2 Biodegradable composite, the preparation process thereof, and a disposable article made therefrom CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2014-10-14 US claimed
US-20120329924-A1 Biodegradable Composite, The Preparation Process Thereof, And A Disposable Article Made Therefrom BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2012-12-27 US claimed
US-10767005-B2 Bibenzoate copolyesters and methods to produce them EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-09-08 US disclosed
US-10759900-B1 Liquid crystalline polyester compositions and methods EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-09-01 US disclosed
US-10759900-B1 Liquid crystalline polyester compositions and methods EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-09-01 US disclosed
US-20200270396-A1 LIQUID CRYSTALLINE POLYESTER COMPOSITIONS AND METHODS VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. 2020-08-27 US disclosed
US-20200262970-A1 BIBENZOATE COPOLYESTERS EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-08-20 US disclosed
US-20200262971-A1 TEREPHTHALATE-CO-4,4-BIBENZOATE POLYESTERS EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-08-20 US disclosed
EP-3551607-A1 BIBENZOATE COPOLYESTERS AND METHODS TO PRODUCE THEM ExxonMobil Chemical Patents Inc. (US) 2019-10-16 EP disclosed
US-20190276592-A1 DIACID MODIFIED COPOLYESTERS EXXONMOBIL CHEMICAL PATENTS INC (US) 2019-09-12 US disclosed
EP-3394130-A1 TEREPHTHALATE-CO-BIBENZOATE POLYESTERS ExxonMobil Chemical Patents Inc. (US) 2018-10-31 EP disclosed
WO-2017112031-A1 TEREPHTHALATE-CO-BIBENZOATE POLYESTERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-06-29 WO disclosed
US-8859690-B2 Biodegradable composite, the preparation process thereof, and a disposable article made therefrom CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2014-10-14 US disclosed
US-20120329924-A1 Biodegradable Composite, The Preparation Process Thereof, And A Disposable Article Made Therefrom BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2012-12-27 US disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-5138022-A Fibers, films, molding materials THE DOW CHEMICAL COMPANY (US) 1992-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 CA12 1221/4885CA9 1228/4885CA1 550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.