Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6893102 | 1.00 | KCNH2 (0.48) | KCNH2MAPTCYP19A1RAB9ANPC1 | |
| SCHEMBL6893109 | 1.00 | KCNH2 (0.48) | KCNH2MAPTCYP19A1RAB9ANPC1 | |
| SCHEMBL6579244 | 0.87 | KCNH2 (0.67) | KCNH2MAPTRAB9ANPC1LMNA | |
| SCHEMBL6579258 | 0.87 | KCNH2 (0.67) | KCNH2MAPTRAB9ANPC1LMNA | |
| SCHEMBL6579255 | 0.87 | KCNH2 (0.67) | KCNH2MAPTRAB9ANPC1LMNA | |
| SCHEMBL6166252 | 0.81 | KCNH2 (0.49) | KCNH2MAPTCYP19A1RAB9ANPC1 | |
| SCHEMBL6166248 | 0.81 | KCNH2 (0.49) | KCNH2MAPTCYP19A1RAB9ANPC1 | |
| SCHEMBL6166243 | 0.81 | KCNH2 (0.49) | KCNH2MAPTCYP19A1RAB9ANPC1 | |
| SCHEMBL6167720 | 0.81 | KCNH2 (0.49) | KCNH2MAPTCYP19A1RAB9ANPC1 | |
| SCHEMBL6167712 | 0.81 | KCNH2 (0.49) | KCNH2MAPTCYP19A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677371-B1 | ANTIARRHYTHMIA AGENTS SUCH AS 6-ACETYLAMINO-3,4-DIHYDRO-2,2-DIMETHYL-4-(2-PHENYLETHOXY)-2H-1-BENZOPYRAN-3 -OL, USED FOR PROPHYLAXIS OF CARDIOVASCULAR DISORDERS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-01-13 | — | — | US | disclosed |