Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 6/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167716 | 1.00 | KCNH2 (0.49) | KCNH2NPC1RAB9AMAPTKCNA5 | |
| SCHEMBL6167720 | 1.00 | KCNH2 (0.49) | KCNH2NPC1RAB9AMAPTKCNA5 | |
| SCHEMBL6166252 | 0.97 | KCNH2 (0.49) | KCNH2NPC1RAB9AMAPTKCNA5 | |
| SCHEMBL6166248 | 0.97 | KCNH2 (0.49) | KCNH2NPC1RAB9AMAPTKCNA5 | |
| SCHEMBL6166243 | 0.97 | KCNH2 (0.49) | KCNH2NPC1RAB9AMAPTKCNA5 | |
| SCHEMBL6807010 | 0.87 | KCNH2 (0.49) | KCNH2MAPTABCB1ALDH1A1LMNA | |
| SCHEMBL6922866 | 0.87 | KCNH2 (0.49) | KCNH2MAPTABCB1ALDH1A1LMNA | |
| SCHEMBL6807009 | 0.87 | KCNH2 (0.49) | KCNH2MAPTABCB1ALDH1A1LMNA | |
| SCHEMBL6172086 | 0.87 | KCNH2 (0.53) | KCNH2MAPTKCNA5MEN1KMT2A | |
| SCHEMBL6172074 | 0.87 | KCNH2 (0.53) | KCNH2MAPTKCNA5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212314-B1 | BENZOPYRAN DERIVATIVE | NISSAN CHEMICAL IND LTD (JP) | 2005-11-30 | — | — | EP | disclosed |
| US-6589983-B1 | Antiarrhythmic agents having the prolongation effect on the functional refractory period as a main function | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2003-07-08 | — | — | US | disclosed |
| EP-1212314-A1 | BENZOPYRAN DERIVATIVE | Nissan Chemical Industries, Ltd. (JP) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001021610-A1 | BENZOPYRAN DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-03-29 | — | — | WO | disclosed |