Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.48 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4479861 | 0.93 | LPAR3 (0.48) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL27430832 | 0.89 | LPAR3 (0.55) | LPAR3LPAR1LPAR2TSHRNAAA | |
| SCHEMBL6739566 | 0.89 | LPAR3 (0.55) | LPAR3LPAR1LPAR2TSHRNAAA | |
| SCHEMBL6733974 | 0.89 | LPAR3 (0.55) | LPAR3LPAR1LPAR2TSHRNAAA | |
| SCHEMBL6734330 | 0.89 | LPAR3 (0.55) | LPAR3LPAR1LPAR2TSHRNAAA | |
| Phosphoric Acid SCHEMBL9775484 | 0.82 | MEN1 (0.64) | MEN1THRBHTTKMT2AMAPT | |
| Phosphoric Acid SCHEMBL9775469 | 0.82 | MEN1 (0.64) | MEN1THRBHTTKMT2AMAPT | |
| Phosphoric Acid SCHEMBL9775464 | 0.82 | MEN1 (0.64) | MEN1THRBHTTKMT2AMAPT | |
| Phosphoric Acid SCHEMBL10667393 | 0.82 | MEN1 (0.64) | MEN1THRBHTTKMT2AMAPT | |
| Phosphoric Acid SCHEMBL10901069 | 0.82 | MEN1 (0.64) | MEN1THRBHTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792275-B1 | IMPROVED ANTIVIRAL PRODRUGS | UNIV CALIFORNIA (US) | 2004-03-03 | — | — | EP | disclosed |
| US-6002029-A | Antiviral prodrugs | CHIMERIX, INC. | 1999-12-14 | — | — | US | disclosed |
| EP-0792275-A4 | IMPROVED ANTIVIRAL PRODRUGS | UNIV CALIFORNIA (US) | 1998-02-25 | — | — | EP | disclosed |
| US-5696277-A | CYTOMEGALOVIRUS, HERPES VIRUS | Hostetler, Karl Y. (US) | 1997-12-09 | — | — | US | disclosed |
| EP-0792275-A1 | IMPROVED ANTIVIRAL PRODRUGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996015132-A1 | IMPROVED ANTIVIRAL PRODRUGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-05-23 | — | — | WO | disclosed |