Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.55 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.55 |
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6733974 | 1.00 | LPAR3 (0.55) | LPAR3LPAR1LPAR2NAAAEPHX1 | |
| SCHEMBL6739566 | 1.00 | LPAR3 (0.55) | LPAR3LPAR1LPAR2NAAAEPHX1 | |
| SCHEMBL6734330 | 1.00 | LPAR3 (0.55) | LPAR3LPAR1LPAR2NAAAEPHX1 | |
| SCHEMBL4479861 | 0.93 | LPAR3 (0.48) | LPAR3LPAR1LPAR2NAAAEPHX1 | |
| SCHEMBL8465669 | 0.91 | ALDH1A1 (0.54) | LPAR3LPAR1LPAR2NAAAEPHX1 | |
| Butane SCHEMBL2239751 | 0.89 | ALDH1A1 (0.52) | LPAR3LPAR1LPAR2NAAAEPHX1 | |
| SCHEMBL6893233 | 0.89 | MEN1 (0.50) | LPAR3LPAR1LPAR2NAAAEPHX1 | |
| SCHEMBL6741785 | 0.80 | NAAA (0.52) | LPAR3LPAR1LPAR2NAAAEPHX1 | |
| SCHEMBL6740544 | 0.80 | NAAA (0.52) | LPAR3LPAR1LPAR2NAAAEPHX1 | |
| SCHEMBL6734697 | 0.80 | NAAA (0.52) | LPAR3LPAR1LPAR2NAAAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1085672-C | Phospholipid derivatives of phosphono-carboxylic acids, prodn. and use as antiviral | ROCHE DIAGNOSTICS GMBH (DE) | 2002-05-29 | — | — | CN | disclosed |
| CN-1209133-A | Novel phospholipid derivatives of phosphonocarboxylic acids, method for the production thereof and use thereof as antiviral agents | BOEHRINGER MANNHEIM GMBH (DE) | 1999-02-24 | — | — | CN | disclosed |
| CN-1209069-A | Covalent lipit-phosphono-carboxylic acid conjugates and application thereof as antiviral medicaments | BOEHRINGER MANNHEIM GMBH (DE) | 1999-02-24 | — | — | CN | disclosed |