Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688620 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2EPHX1HSD11B1KMT2AALDH1A1 | |
| SCHEMBL688621 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2EPHX1HSD11B1KMT2AALDH1A1 | |
| SCHEMBL2667367 | 0.78 | EPHX2 (0.40) | EPHX1KMT2AALDH1A1MEN1EPHX2 | |
| SCHEMBL12384847 | 0.76 | EPHX2 (0.50) | EPHX1EPHX2 | |
| SCHEMBL687588 | 0.72 | ALDH1A1 (0.43) | EPHX1KMT2AALDH1A1MEN1TSHR | |
| SCHEMBL12384849 | 0.71 | NPSR1 (0.48) | SMN1; SMN2EPHX1KMT2AALDH1A1MEN1 | |
| SCHEMBL9071835 | 0.71 | NPSR1 (0.48) | SMN1; SMN2EPHX1KMT2AALDH1A1MEN1 | |
| SCHEMBL9071824 | 0.69 | ALDH1A1 (0.46) | SMN1; SMN2EPHX1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL8598891 | 0.69 | EPHX1 (0.75) | SMN1; SMN2EPHX1ALDH1A1CYP3A4EPHX2 | |
| SCHEMBL8598712 | 0.69 | EPHX1 (0.75) | SMN1; SMN2EPHX1ALDH1A1CYP3A4EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904438-B1 | DICYCLOALKYLCARBAMOYL UREAS AS GLUCOKINASE ACTIVATORS | NOVO NORDISK AS (DK) | 2012-02-29 | — | — | EP | claimed |