Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6893817 | 1.00 | CACNA1C (0.35) | CACNA1CESR1PTGS1PDE4A | |
| SCHEMBL6886821 | 1.00 | CACNA1C (0.35) | CACNA1CESR1PTGS1PDE4A | |
| SCHEMBL6887231 | 1.00 | CACNA1C (0.35) | CACNA1CESR1PTGS1PDE4A | |
| SCHEMBL7722261 | 0.92 | ABCC2 (0.32) | — | |
| SCHEMBL6887472 | 0.92 | CACNA1C (0.38) | CACNA1CESR1PTGS1PDE4A | |
| SCHEMBL6891539 | 0.91 | CACNA1C (0.36) | CACNA1CESR1PTGS1PDE4A | |
| SCHEMBL6894691 | 0.90 | CACNA1C (0.34) | CACNA1CESR1PTGS1PDE4A | |
| SCHEMBL6887058 | 0.90 | CACNA1C (0.34) | CACNA1CESR1PTGS1PDE4A | |
| SCHEMBL6896064 | 0.90 | CACNA1C (0.34) | CACNA1CESR1PTGS1PDE4A | |
| SCHEMBL6889765 | 0.90 | CACNA1C (0.36) | CACNA1CESR1PTGS1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677331-B2 | HAVING SUBSTITUTED IMIDAZO(5,1-B)THIAZOLE GROUP AT 2-POSITION; MICROBIOCIDES AGAINST BETA-LACTAMASE PRODUCING BACTERIA AND RESISTANT PSEUDOMONAS | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-01-13 | — | — | US | disclosed |