Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6770488 | 1.00 | CACNA1C (0.34) | CACNA1CESR1PTGS1PDE4AABCC2 | |
| SCHEMBL6895949 | 1.00 | CACNA1C (0.34) | CACNA1CESR1PTGS1PDE4AABCC2 | |
| SCHEMBL6772192 | 1.00 | CACNA1C (0.34) | CACNA1CESR1PTGS1PDE4AABCC2 | |
| SCHEMBL7728165 | 0.92 | ABCC2 (0.34) | ABCC2 | |
| SCHEMBL6767979 | 0.92 | CACNA1C (0.35) | CACNA1CESR1PTGS1PDE4AABCC2 | |
| SCHEMBL6771009 | 0.90 | CACNA1C (0.34) | CACNA1CESR1PTGS1PDE4A | |
| SCHEMBL6622856 | 0.89 | ESR1 (0.33) | CACNA1CESR1PTGS1PDE4A | |
| SCHEMBL6771850 | 0.89 | CACNA1C (0.34) | CACNA1CESR1PTGS1PDE4A | |
| SCHEMBL6624812 | 0.88 | CACNA1C (0.34) | CACNA1CESR1PTGS1PDE4A | |
| SCHEMBL6772792 | 0.88 | CACNA1C (0.34) | CACNA1CESR1PTGS1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677331-B2 | HAVING SUBSTITUTED IMIDAZO(5,1-B)THIAZOLE GROUP AT 2-POSITION; MICROBIOCIDES AGAINST BETA-LACTAMASE PRODUCING BACTERIA AND RESISTANT PSEUDOMONAS | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-01-13 | — | — | US | disclosed |