Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10768544 | 1.00 | ELANE (0.48) | ELANEHTR2AALDH1A1MAPTHPGD | |
| SCHEMBL10675931 | 1.00 | ELANE (0.48) | ELANEHTR2AALDH1A1MAPTHPGD | |
| SCHEMBL14875217 | 1.00 | ELANE (0.48) | ELANEHTR2AALDH1A1MAPTHPGD | |
| SCHEMBL2062622 | 1.00 | ELANE (0.48) | ELANEHTR2AALDH1A1MAPTHPGD | |
| SCHEMBL9039878 | 1.00 | ELANE (0.48) | ELANEHTR2AALDH1A1MAPTHPGD | |
| SCHEMBL18036888 | 1.00 | ELANE (0.48) | ELANEHTR2AALDH1A1MAPTHPGD | |
| SCHEMBL10767245 | 1.00 | ELANE (0.48) | ELANEHTR2AALDH1A1MAPTHPGD | |
| SCHEMBL10758551 | 1.00 | ELANE (0.48) | ELANEHTR2AALDH1A1MAPTHPGD | |
| SCHEMBL10670342 | 0.91 | HTR2A (0.43) | ELANEHTR2AALDH1A1MAPTHPGD | |
| SCHEMBL10676045 | 0.91 | HTR2A (0.43) | ELANEHTR2AALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677331-B2 | HAVING SUBSTITUTED IMIDAZO(5,1-B)THIAZOLE GROUP AT 2-POSITION; MICROBIOCIDES AGAINST BETA-LACTAMASE PRODUCING BACTERIA AND RESISTANT PSEUDOMONAS | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-01-13 | — | — | US | disclosed |
| US-6458780-B1 | IMIDAZO(5,1-B)THIAZOLE GROUP AT THE 2-POSITION ON THE CARBAPENEM RING HAVE HIGH ANTI-MICROBIAL ACTIVITIES AGAINST .BETA.-LACTAMASE PRODUCING BACTERIA, MRSA, RESISTANT-PSEUDOMONAS AERUGINOSA, PRSP, ENTEROCOCCI, AND | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-10-01 | — | — | US | disclosed |