Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10768544 | 1.00 | ELANE (0.48) | ELANEHTR2AALDH1A1MAPTHPGD | |
| SCHEMBL10675931 | 1.00 | ELANE (0.48) | ELANEHTR2AALDH1A1MAPTHPGD | |
| SCHEMBL14875217 | 1.00 | ELANE (0.48) | ELANEHTR2AALDH1A1MAPTHPGD | |
| SCHEMBL2062622 | 1.00 | ELANE (0.48) | ELANEHTR2AALDH1A1MAPTHPGD | |
| SCHEMBL18036888 | 1.00 | ELANE (0.48) | ELANEHTR2AALDH1A1MAPTHPGD | |
| SCHEMBL10767245 | 1.00 | ELANE (0.48) | ELANEHTR2AALDH1A1MAPTHPGD | |
| SCHEMBL6893609 | 1.00 | ELANE (0.48) | ELANEHTR2AALDH1A1MAPTHPGD | |
| SCHEMBL10758551 | 1.00 | ELANE (0.48) | ELANEHTR2AALDH1A1MAPTHPGD | |
| SCHEMBL10670342 | 0.91 | HTR2A (0.43) | ELANEHTR2AALDH1A1MAPTHPGD | |
| SCHEMBL10676045 | 0.91 | HTR2A (0.43) | ELANEHTR2AALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442497-B1 | Novel beta-lactam compounds and their production | SUMITOMO PHARMA (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0658162-A1 | CARBAPENEM DERIVATIVES AND PROCESSES FOR PREPARING THE SAME | DONG-A PHARM. CO., LTD. (KR) | 1995-06-21 | — | — | EP | disclosed |
| EP-0126587-B1 | Carboxylic thio-pyrrolidinyl beta-lactam compounds and production thereof | SUMITOMO PHARMA (JP) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994005667-A1 | CARBAPENEM DERIVATIVES AND PROCESSES FOR PREPARING THE SAME | DONG-A PHARMACEUTICAL CO., LTD. (KR) | 1994-03-17 | — | — | WO | disclosed |
| US-5227376-A | Quaternary ammonium carbapenem antibiotics | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| US-5122604-A | 2-(2-Carbonyl-substituted pyrrolidin-4-yl)carbapenems and -penems; microbiocides | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1992-06-16 | — | — | US | disclosed |
| EP-0442497-A1 | Novel beta-lactam compounds and their production | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4962103-A | MICROBIOCIDES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0182213-B1 | CARBAPENEM COMPOUNDS AND PRODUCTION THEREOF | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1990-09-26 | — | — | EP | disclosed |
| US-4943569-A | B-lactam compounds | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1990-07-24 | — | — | US | disclosed |
| US-4933333-A | β-lactam compounds | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0188816-A1 | Novel beta-lactams and their production | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1986-07-30 | — | — | EP | disclosed |
| EP-0182213-A1 | Carbapenem compounds and production thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1986-05-28 | — | — | EP | disclosed |
| EP-0126587-A1 | Carboxylic thio-pyrrolidinyl beta-lactam compounds and production thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1984-11-28 | — | — | EP | disclosed |