Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 4/20 | 0.44 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 14/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19747754 | 0.85 | BCHE (0.59) | IMPDH2IMPDH1BCHECTSLCES2 | |
| SCHEMBL12368240 | 0.80 | IMPDH2 (0.51) | IMPDH2IMPDH1BCHECTSLCES2 | |
| SCHEMBL14518603 | 0.79 | IMPDH2 (0.52) | IMPDH2IMPDH1BCHECTSLLMNA | |
| SCHEMBL13202467 | 0.79 | BCHE (0.53) | IMPDH2IMPDH1BCHECTSLMLNR | |
| SCHEMBL12368238 | 0.78 | IMPDH2 (0.49) | IMPDH2IMPDH1BCHECTSLLMNA | |
| SCHEMBL14543430 | 0.76 | IMPDH2 (0.50) | IMPDH2IMPDH1BCHECTSLCTSD | |
| SCHEMBL2969565 | 0.75 | BCHE (0.53) | IMPDH2IMPDH1BCHE | |
| SCHEMBL2969563 | 0.75 | BCHE (0.53) | IMPDH2IMPDH1BCHE | |
| SCHEMBL25274986 | 0.73 | TSHR (0.49) | CYP3A4 | |
| SCHEMBL2972427 | 0.72 | IMPDH2 (0.55) | IMPDH2IMPDH1BCHECTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022554-A1 | QUINAZOLINONE DERIVATIVES | CELLTECH R & D LIMITED (GB) | 2004-03-18 | — | — | WO | disclosed |