Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.67 |
| ▸ | MMP8 | P22894 | 7/20 | 0.67 |
| ▸ | MMP2 | P08253 | 6/20 | 0.67 |
| ▸ | MMP10 | P09238 | 5/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4373943 | 0.87 | MMP13 (0.79) | MMP13MMP8MMP2MMP10 | |
| SCHEMBL10290012 | 0.84 | MMP13 (0.76) | MMP13MMP8MMP2MMP10 | |
| SCHEMBL10289587 | 0.83 | MMP13 (0.70) | MMP13MMP8MMP2MMP10 | |
| Hydrochloric Acid SCHEMBL689705 | 0.83 | MMP13 (0.75) | MMP13MMP8MMP2MMP10 | |
| SCHEMBL688986 | 0.82 | MMP13 (0.73) | MMP13MMP8MMP2MMP10 | |
| SCHEMBL688841 | 0.81 | MMP13 (0.72) | MMP13MMP8MMP2MMP10 | |
| SCHEMBL4934733 | 0.80 | MMP13 (0.72) | MMP13MMP8MMP2MMP10 | |
| SCHEMBL689779 | 0.77 | MMP13 (0.64) | MMP13MMP8MMP2MMP10 | |
| SCHEMBL689477 | 0.77 | MMP13 (0.72) | MMP13MMP8MMP2MMP10 | |
| SCHEMBL689176 | 0.77 | MMP13 (0.74) | MMP13MMP8MMP2MMP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953148-B1 | HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-7915267-B2 | Heterocyclic amide compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-03-29 | — | — | US | disclosed |