Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7198503 | 0.79 | TSHR (0.48) | HSD17B10CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL253635 | 0.77 | HSD17B10 (0.41) | HSD17B10CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL31201820 | 0.75 | HSD17B10 (0.63) | HSD17B10CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL2162162 | 0.75 | IMPDH2 (0.61) | HSD17B10CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL28270200 | 0.75 | HPGD (0.44) | HSD17B10CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8637918 | 0.75 | HSD17B10 (0.40) | HSD17B10CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL301407 | 0.75 | HSD17B10 (0.40) | HSD17B10CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL1325658 | 0.75 | HSD17B10 (0.63) | HSD17B10CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL2533977 | 0.75 | HSD17B10 (0.40) | HSD17B10CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7924281 | 0.75 | HSD17B10 (0.40) | HSD17B10CYP1A2CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235023-A1 | Parallel combinatorial approach to the discovery and optimization of catalysts and uses thereof | JACOBSEN ERIC N (US) | 2004-11-25 | — | — | US | disclosed |
| US-6709824-B2 | SCREENING SAMPLE FOR CATALYST; GENERATE LIBRARY OF CATALYST, SCREEN LIBRARY, RECOVER CATALYST | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2004-03-23 | — | — | US | disclosed |
| US-20020102612-A1 | Parallel combinatorial approach to the discovery and optimization of catalysts and uses thereof | JACOBSEN ERIC N (US) | 2002-08-01 | — | — | US | disclosed |
| US-6316616-B1 | USED AS CATALYST TO CATALYZE A CHEMOSELECTIVE, REGIOSELECTIVE, STEREOSELECTIVE OR ENANTIOSELECTIVE TRANSFORMATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2001-11-13 | — | — | US | disclosed |
| EP-1066228-A1 | PARALLEL COMBINATORIAL APPROACH TO THE DISCOVERY AND OPTIMIZATION OF CATALYSTS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999051546-A9 | PARALLEL COMBINATORIAL APPROACH TO THE DISCOVERY AND OPTIMIZATION OF CATALYSTS AND USES THEREOF | HARVARD COLLEGE (US) | 1999-11-18 | — | — | WO | disclosed |
| WO-1999051546-A1 | PARALLEL COMBINATORIAL APPROACH TO THE DISCOVERY AND OPTIMIZATION OF CATALYSTS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1999-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020102612-A1 | Parallel combinatorial approach to the discovery and optimization of catalysts and uses thereof | COASY, DCXR, LSS | HSD17B10 186/4885CYP1A2 94/4885CYP2C9 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.