Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ELOVL1 | Q9BW60 | 2/20 | 0.40 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971231 | 0.82 | CYP2C9 (0.46) | MEN1KMT2AELOVL1HTTLMNA | |
| SCHEMBL28013624 | 0.78 | ABCB11 (0.43) | ELOVL1HTTLMNACYP2C9ALDH1A1 | |
| SCHEMBL5823369 | 0.72 | ABCB11 (0.51) | MEN1KMT2AELOVL1HTTCYP2C9 | |
| SCHEMBL7757989 | 0.72 | CYP2C9 (0.43) | MEN1KMT2AELOVL1HTTLMNA | |
| SCHEMBL28330107 | 0.71 | CYP2C9 (0.40) | ELOVL1HTTLMNACYP2C9ALDH1A1 | |
| SCHEMBL24891484 | 0.71 | ADORA2A (0.35) | MEN1KMT2AHTTCYP2C9ALDH1A1 | |
| SCHEMBL30278611 | 0.71 | ADORA2A (0.35) | MEN1KMT2AHTTCYP2C9ALDH1A1 | |
| SCHEMBL29503091 | 0.69 | CYP2C9 (0.47) | KMT2AELOVL1HTTLMNACYP2C9 | |
| SCHEMBL2044641 | 0.69 | MEN1 (0.59) | MEN1KMT2ARHEBHTTLMNA | |
| SCHEMBL28830073 | 0.69 | TAAR1 (0.44) | CYP2C9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501270-B | A kind of compound containing sulphonyl ethylene imine structure, pharmaceutical composition and its application | 宏腾建设集团有限公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-107501270-A | A kind of compound containing sulphonyl ethylene imine structure, pharmaceutical composition and its application | 南京宏腾建设工程有限公司 | 2017-12-22 | — | — | CN | disclosed |
| US-6737418-B2 | CENTRAL NERVOUS SYSTEM DISORDERS; ANTICONVULSANTS | EURO-CELTIQUE S.A. (LU) | 2004-05-18 | — | — | US | disclosed |