Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1774091 | 0.84 | NPC1 (0.45) | EPHX1HIF1ARAB9ANPC1ALDH1A1 | |
| SCHEMBL16424555 | 0.81 | EPHX1 (0.44) | EPHX1HIF1AMCL1RAB9ANPC1 | |
| SCHEMBL29831394 | 0.79 | NPC1 (0.48) | EPHX1HIF1ARAB9ANPC1ALDH1A1 | |
| SCHEMBL1774092 | 0.79 | NPC1 (0.48) | EPHX1HIF1ARAB9ANPC1ALDH1A1 | |
| SCHEMBL5168305 | 0.78 | MCL1 (0.43) | MCL1RAB9ANPC1KMOALDH1A1 | |
| SCHEMBL8394538 | 0.78 | MCL1 (0.43) | MCL1RAB9ANPC1KMOALDH1A1 | |
| SCHEMBL8396555 | 0.78 | MCL1 (0.43) | MCL1RAB9ANPC1KMOALDH1A1 | |
| SCHEMBL3033731 | 0.75 | MCL1 (0.44) | MCL1RAB9ANPC1KMOALDH1A1 | |
| SCHEMBL414294 | 0.73 | EPHX1 (0.40) | EPHX1HIF1AMCL1RAB9ANPC1 | |
| SCHEMBL8396484 | 0.72 | TDP1 (0.41) | MCL1RAB9ANPC1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040097734-A1 | Aryl- and heteroarylcarbonylpiperazines and their use for the treatment of benign and malignant oncoses | ZENTARIS GMBH (DE) | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097734-A1 | Aryl- and heteroarylcarbonylpiperazines and their use for the treatment of benign and malignant oncoses | VHL, MYC, HCCS | EPHX1 645/4885HIF1A 825/4885MCL1 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.