Sugi Predict

Sugi Predict / Compounds / SCHEMBL414294

SCHEMBL414294

SCHEMBL414294

C(=NC1CCCCC1)=C(c1ccccc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EPHX1 P07099 1/20 0.40
▸ HIF1A Q16665 1/20 0.40
▸ ALDH1A1 P00352 3/20 0.38
▸ MEN1 O00255 3/20 0.37
▸ KMT2A Q03164 3/20 0.37
▸ ALOX15 P16050 1/20 0.37
▸ MCL1 Q07820 1/20 0.35
▸ RAB9A P51151 3/20 0.35
▸ NPC1 O15118 2/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ TP53 P04637 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ ALOX12 P18054 1/20 0.35
▸ SIGMAR1 Q99720 3/20 0.34
▸ KMO O15229 1/20 0.34
▸ POLB P06746 1/20 0.34
▸ ELANE P08246 1/20 0.34
▸ TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17021222 0.83 ALDH1A1 (0.46) ALDH1A1MEN1KMT2ARAB9ANPC1
SCHEMBL29898233 0.74 LMNA (0.39) ALDH1A1MEN1KMT2ARAB9ANPC1
SCHEMBL16424555 0.73 EPHX1 (0.44) EPHX1HIF1AALDH1A1MEN1KMT2A
SCHEMBL6894162 0.73 EPHX1 (0.44) EPHX1HIF1AALDH1A1MEN1KMT2A
SCHEMBL10453742 0.72 EPHX1 (0.52) EPHX1HIF1AALDH1A1ALOX15MAPT
SCHEMBL8547998 0.71 ALDH1A1 (0.47) ALDH1A1MEN1KMT2AALOX15MCL1
SCHEMBL30762071 0.71 ALDH1A1 (0.47) ALDH1A1MEN1KMT2AALOX15MCL1
SCHEMBL4392357 0.71 MEN1 (0.49) ALDH1A1MEN1KMT2AALOX15MCL1
SCHEMBL30762062 0.71 ALDH1A1 (0.47) ALDH1A1MEN1KMT2AALOX15MCL1
SCHEMBL28215461 0.69 EPHX1 (0.48) EPHX1HIF1AALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1063 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0004570-B1 THIOL ESTERS, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND A PROCESS FOR PREPARING CEPHALOSPORIN COMPOUNDS USING THE SAME Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-04-14 — — EP claimed
EP-0004570-A1 Thiol esters, process for their preparation, pharmaceutical compositions containing them and a process for preparing cephalosporin compounds using the same Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1979-10-17 — — EP claimed
US-20260108497-A1 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION OTSUKA PHARMACEUTICALC., LTD. (JP) 2026-04-23 — — US disclosed
EP-4707284-A1 HETEROCYCLIC COMPOUND AND USE THEREOF Otsuka Pharmaceutical Co., Ltd. (JP) 2026-03-11 — — EP disclosed
WO-2025089370-A1 COMPOUNDS AS CSF1R INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2025-05-01 — — WO disclosed
US-20250051310-A1 BENZAZEPINE DERIVATIVES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2025-02-13 — — US disclosed
WO-2024228399-A1 HETEROCYCLIC COMPOUND AND USE THEREOF 大塚製薬株式会社 2024-11-07 — — WO disclosed
US-20240286999-A1 AZABICYCLO[3.1.0]HEXANE COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2024-08-29 — — US disclosed
US-20240148699-A1 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2024-05-09 — — US disclosed
EP-4357335-A1 AZABICYCLO[3.1.0]HEXANE COMPOUND Otsuka Pharmaceutical Co., Ltd. (JP) 2024-04-24 — — EP disclosed
CN-117480153-A Azabicyclo [3.1.0] hexane compounds 大塚制药株式会社 2024-01-30 — — CN disclosed
US-4058523-A ANTIULCER, VASODILATION, HYPOTENSIVE, ANALGESIC CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) 1977-11-15 — — US disclosed
US-4039536-A 7-(α-SUBSTITUTED GLYCINAMIDO)-3-SUBSTITUTED METHYL-3-CEPHEM-4-CARBOXYLIC ACIDS AND THEIR DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-08-02 — — US disclosed
US-4016160-A BACTERICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-04-05 — — US disclosed
US-4001280-A ANTIALLERGENS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-01-04 — — US disclosed
US-4001225-A Pyridyl substituted 7-αesters of 3 heterothio 7-acetamido cephalosporanic acids FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-01-04 — — US disclosed
US-4000133-A BACTERICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-12-28 — — US disclosed
US-3992409-A ANTICOLINERGIC AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-11-16 — — US disclosed
US-3984397-A CYCLIZATION FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-10-05 — — US disclosed
US-3954732-A BACTERICIDAL PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-05-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240148699-A1 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION PDE3B, PDE4A, PDE3A EPHX1 490/4885HIF1A 2888/4885ALDH1A1 234/4885
US-20260108497-A1 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION PDE7B, PDE4B, PDE1B EPHX1 2266/4885HIF1A 3904/4885ALDH1A1 923/4885
US-20240286999-A1 AZABICYCLO[3.1.0]HEXANE COMPOUND MALT1, CXCR1, AZI2 EPHX1 96/4885HIF1A 4056/4885ALDH1A1 479/4885
US-20250051310-A1 BENZAZEPINE DERIVATIVES AVPR2, AVPR1A, AVPR1B EPHX1 2637/4885HIF1A 383/4885ALDH1A1 628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.