SCHEMBL6894563

SCHEMBL6894563

CC(C)CN=C=O.CCCCCCN=C=O

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.45
TRPA1 O75762 1/20 0.35
TRPM8 Q7Z2W7 5/20 0.34
ADH1B P00325 1/20 0.32
ADH1C P00326 1/20 0.32
ADH1A P07327 1/20 0.32
ADH4 P08319 1/20 0.32
ADH7 P40394 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TSHR P16473 1/20 0.31
THRB P10828 1/20 0.31
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nonane SCHEMBL3071312 0.85 NAAA (0.58) NAAAMEN1KMT2ATSHRTHRB
SCHEMBL5571386 0.85 NAAA (0.58) NAAAMEN1KMT2ATSHRTHRB
SCHEMBL37419 0.85 NAAA (0.58) NAAAMEN1KMT2ATSHRTHRB
SCHEMBL1493031 0.85 NAAA (0.58) NAAAMEN1KMT2ATSHRTHRB
SCHEMBL10870593 0.85 NAAA (0.58) NAAAMEN1KMT2ATSHRTHRB
SCHEMBL10791564 0.85 NAAA (0.58) NAAAMEN1KMT2ATSHRTHRB
SCHEMBL527174 0.85 NAAA (0.58) NAAAMEN1KMT2ATSHRTHRB
SCHEMBL15486455 0.85 NAAA (0.58) NAAAMEN1KMT2ATSHRTHRB
SCHEMBL5575642 0.85 NAAA (0.58) NAAAMEN1KMT2ATSHRTHRB
Hexane SCHEMBL2866709 0.85 NAAA (0.58) NAAAMEN1KMT2ATSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1126833-A4 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES INC (US) 2004-09-08 EP disclosed
EP-1126833-A2 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES, INC. (US) 2001-08-29 EP disclosed
WO-2000025768-A1 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES, INC. (US) 2000-05-11 WO disclosed