Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 4/20 | 0.59 |
| ▸ | ANPEP | P15144 | 2/20 | 0.59 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.59 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.59 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4689505 | 1.00 | LAP3 (0.59) | LAP3ANPEPRNPEPDNPEPCSNK1E | |
| SCHEMBL5220403 | 0.92 | LAP3 (0.53) | LAP3ANPEPRNPEPDNPEPCSNK1E | |
| SCHEMBL5224141 | 0.90 | CSNK1E (0.55) | LAP3ANPEPRNPEPDNPEPCSNK1E | |
| SCHEMBL1057036 | 0.86 | CSNK1E (0.51) | LAP3ANPEPRNPEPDNPEPCSNK1E | |
| SCHEMBL1286637 | 0.86 | CSNK1E (0.51) | LAP3ANPEPRNPEPDNPEPCSNK1E | |
| SCHEMBL1286638 | 0.86 | CSNK1E (0.51) | LAP3ANPEPRNPEPDNPEPCSNK1E | |
| SCHEMBL4039471 | 0.85 | BCHE (0.58) | CSNK1ESLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL5930069 | 0.85 | CSNK1E (0.57) | LAP3ANPEPRNPEPDNPEPCSNK1E | |
| Hydrochloric Acid SCHEMBL5223863 | 0.85 | CSNK1E (0.50) | LAP3ANPEPRNPEPDNPEPCSNK1E | |
| Hydrochloric Acid SCHEMBL8734228 | 0.85 | CSNK1E (0.50) | LAP3ANPEPRNPEPDNPEPCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |
| US-5708004-A | ENZYME INHIBITORS FOR TREATMENT OF AIDS | MONSANTO COMPANY (US) | 1998-01-13 | — | — | US | disclosed |
| US-5703076-A | TREATING HIV, AIDS | G. D. SEARLE & CO. (US) | 1997-12-30 | — | — | US | disclosed |
| US-5698569-A | Retroviral protease inhibitors | G. D. SEARLE & CO. (US) | 1997-12-16 | — | — | US | disclosed |
| US-5510349-A | HUMAN IMMUNODEFICIENCY VIRUS | G.D. SEARLE & CO. (US) | 1996-04-23 | — | — | US | disclosed |
| US-5510487-A | TREATING HUMAN IMMUNODEFICIENCY VIRUS INFECTIONS | G.D. SEARLE & CO. (US) | 1996-04-23 | — | — | US | disclosed |
| US-5510378-A | Retroviral protease inhibitors | G.D. SEARLE & CO. (US) | 1996-04-23 | — | — | US | disclosed |