Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709153 | 1.00 | HCAR2 (0.59) | HCAR2ATMMAPTNPSR1CA12 | |
| Diethyl Maleate SCHEMBL27966383 | 0.83 | HCAR2 (0.80) | HCAR2ATMMAPTNPSR1CA12 | |
| SCHEMBL6049197 | 0.83 | HCAR2 (0.45) | HCAR2ATMALDH1A1 | |
| SCHEMBL9615496 | 0.83 | HCAR2 (0.45) | HCAR2ATMALDH1A1 | |
| Diethyl Maleate SCHEMBL43033 | 0.83 | HCAR2 (0.80) | HCAR2ATMMAPTNPSR1CA12 | |
| Diethyl Maleate SCHEMBL42602 | 0.83 | HCAR2 (0.80) | HCAR2ATMMAPTNPSR1CA12 | |
| Diethyl Maleate SCHEMBL2015896 | 0.83 | HCAR2 (0.80) | HCAR2ATMMAPTNPSR1CA12 | |
| Diethyl Maleate SCHEMBL60423 | 0.83 | HCAR2 (0.80) | HCAR2ATMMAPTNPSR1CA12 | |
| Diethyl Maleate SCHEMBL2015895 | 0.83 | HCAR2 (0.80) | HCAR2ATMMAPTNPSR1CA12 | |
| SCHEMBL16004844 | 0.83 | HCAR2 (0.45) | HCAR2ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10316046-B2 | Method for producing acyloxysilanes, acyloxysilanes obtained thereby, and use of same | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2019-06-11 | — | — | US | disclosed |
| US-20180044359-A1 | Method for Producing Acyloxysilanes, Acyloxysilanes Obtained Thereby, and Use of Same | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2018-02-15 | — | — | US | disclosed |
| EP-0405537-B1 | N-substituted cycloalkyl and polycycloalkyl alpha-substituted Trp-Phe- and phenethylamine derivatives | WARNER LAMBERT CO (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-0790289-B1 | Polymeric material for liquid crystal/polymer composite film, record display medium, and use thereof | DAINIPPON PRINTING CO LTD (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-5851422-A | Polymeric material for liquid crystal/polymer composite film, record display medium, and use thereof | DAI NIPPON PRINTING CO., LTD. (JP) | 1998-12-22 | — | — | US | disclosed |
| EP-0790289-A1 | Polymeric material for liquid crystal/polymer composite film, liquid crystal/polymer composite film, record display medium, and use thereof | DAI NIPPON PRINTING CO., LTD. (JP) | 1997-08-20 | — | — | EP | disclosed |
| US-5631281-A | COMPOUNDS FOR TREATMENT OF ANXIETY WITH INDOLE AMIDES | WARNER-LAMBERT COMPANY (US) | 1997-05-20 | — | — | US | disclosed |
| US-5622983-A | ANTIOBESITY AGENTS, ANTIPSYCHOTIC AGENTS, ANTIULCER AGENTS | WARNER-LAMBERT COMPANY (US) | 1997-04-22 | — | — | US | disclosed |
| US-5580896-A | Treatment of pain and colorectal cancer with dipeptoids of α-substituted Trp-Phe derivatives | WARNER-LAMBERT COMPANY (US) | 1996-12-03 | — | — | US | disclosed |
| US-5278316-A | Indoles | WARNER-LAMBERT COMPANY (US) | 1994-01-11 | — | — | US | disclosed |
| EP-0479910-A1 | N-SUBSTITUTED CYCLOALKYL AND POLYCYCLOALKYL ALPHA-SUBSTITUTED Trp-Phe- AND PHENETHYLAMINE DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1992-04-15 | — | — | EP | disclosed |
| WO-1991000274-A1 | N-SUBSTITUTED CYCLOALKYL AND POLYCYCLOALKYL ALPHA-SUBSTITUTED TRP-PHE- AND PHENETHYLAMINE DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1991-01-10 | — | — | WO | disclosed |
| EP-0405537-A1 | N-substituted cycloalkyl and polycycloalkyl alpha-substituted Trp-Phe- and phenethylamine derivatives | WARNER-LAMBERT COMPANY (US) | 1991-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044359-A1 | Method for Producing Acyloxysilanes, Acyloxysilanes Obtained Thereby, and Use of Same | COASY, AGPS, CA7 | HCAR2 443/4885ATM 2679/4885MAPT 4750/4885 |
| US-10316046-B2 | Method for producing acyloxysilanes, acyloxysilanes obtained thereby, and use of same | COASY, AGPS, CA7 | HCAR2 443/4885ATM 2679/4885MAPT 4750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.