Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6895301 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2CA14CA12ALDH1A1MEN1 | |
| SCHEMBL6895304 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2CA14CA12ALDH1A1MEN1 | |
| SCHEMBL188811 | 0.80 | SMN1; SMN2 (0.70) | SMN1; SMN2CA14CA12ALDH1A1MEN1 | |
| SCHEMBL3380774 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2CA14CA12ALDH1A1MEN1 | |
| SCHEMBL6897235 | 0.73 | SLC7A5 (0.42) | — | |
| SCHEMBL6446523 | 0.73 | SMN1; SMN2 (0.61) | SMN1; SMN2CA14CA12ALDH1A1KMT2A | |
| SCHEMBL856080 | 0.73 | SMN1; SMN2 (0.61) | SMN1; SMN2CA14CA12ALDH1A1MEN1 | |
| SCHEMBL4616218 | 0.71 | SMN1; SMN2 (0.71) | SMN1; SMN2CA14CA12ALDH1A1MEN1 | |
| SCHEMBL19105452 | 0.70 | SMN1; SMN2 (0.64) | SMN1; SMN2CA14CA12ALDH1A1MEN1 | |
| SCHEMBL20657106 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | disclosed |