Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28290844 | 0.87 | ESR1 (0.56) | ESR1ESR2ATMCYP1A2CYP2C9 | |
| SCHEMBL28289374 | 0.87 | ESR1 (0.56) | ESR1ESR2ATMCYP1A2CYP2C9 | |
| SCHEMBL28290841 | 0.87 | ESR1 (0.56) | ESR1ESR2ATMCYP1A2CYP2C9 | |
| SCHEMBL28289373 | 0.85 | ESR1 (0.59) | ESR1ESR2ATMCYP1A2CYP2C9 | |
| SCHEMBL28289375 | 0.82 | ESR1 (0.51) | ESR1ESR2ATMKIF11ALDH1A1 | |
| SCHEMBL15700643 | 0.82 | ESR1 (0.56) | ESR1ESR2ATMSMN1; SMN2HIF1A | |
| SCHEMBL15700645 | 0.82 | ESR1 (0.51) | ESR1ESR2ATMCYP1A2CYP2C9 | |
| SCHEMBL15700641 | 0.80 | ESR1 (0.49) | ESR1ESR2ATMCYP1A2CYP2C19 | |
| SCHEMBL15700648 | 0.80 | ESR1 (0.53) | ESR1ESR2ATMCYP1A2CYP2C9 | |
| SCHEMBL19143618 | 0.79 | ESR1 (0.44) | ESR1ESR2ATMCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10292388-B2 | Malononitrile compounds for controlling animal pests | BASF SE (DE) | 2019-05-21 | — | — | US | disclosed |
| EP-2911509-B1 | MALONONITRILE COMPOUNDS FOR CONTROLLING ANIMAL PESTS | BASF SE (DE) | 2017-07-19 | — | — | EP | disclosed |
| US-20170027899-A1 | USE OF MALONONITRILE COMPOUNDS FOR PROTECTING ANIMALS FROM PARASITES | MERIAL INC. (US) | 2017-02-02 | — | — | US | disclosed |
| WO-2015161224-A1 | USE OF MALONONITRILE COMPOUNDS FOR PROTECTING ANIMALS FROM PARASITES | MERIAL, INC. (US) | 2015-10-22 | — | — | WO | disclosed |
| US-20150282481-A1 | MALONONITRILE COMPOUNDS FOR CONTROLLING ANIMAL PESTS | BASF SE (DE) | 2015-10-08 | — | — | US | disclosed |
| WO-2014064093-A1 | MALONONITRILE COMPOUNDS FOR CONTROLLING ANIMAL PESTS | BASF SE (DE) | 2014-05-01 | — | — | WO | disclosed |
| US-6783796-B2 | Method of manufacturing an electronic device | KABUSHIKI KAISHA TOSHIBA (JP) | 2004-08-31 | — | — | US | disclosed |
| US-20030087064-A1 | Electronic device and method of manufacturing the same | KABUSHIKI KAISHA TOSHIBA (JP) | 2003-05-08 | — | — | US | disclosed |
| US-6447879-B1 | Electronic Device and method of manufacturing the same | KABUSHIKI KAISHA TOSHIBA (JP) | 2002-09-10 | — | — | US | disclosed |
| US-3984452-A | Process for the preparation of a p,p'-dicyanobibenzyl and a m,m'-dicyanobibenzyl | AKZONA INCORPORATED (US) | 1976-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170027899-A1 | USE OF MALONONITRILE COMPOUNDS FOR PROTECTING ANIMALS FROM PARASITES | MAL2, NAT1, ME1 | ESR1 4336/4885ESR2 4457/4885ATM 4765/4885 |
| US-10292388-B2 | Malononitrile compounds for controlling animal pests | MAL2, ME1, DDT | ESR1 4781/4885ESR2 4818/4885ATM 3817/4885 |
| US-20150282481-A1 | MALONONITRILE COMPOUNDS FOR CONTROLLING ANIMAL PESTS | MAL2, ME1, DDT | ESR1 4781/4885ESR2 4818/4885ATM 3817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.