Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3351836 | 1.00 | BCHE (0.53) | BCHEGAADNM1OPRD1OPRK1 | |
| SCHEMBL3353939 | 0.91 | BCHE (0.61) | BCHEDNM1OPRD1OPRK1ANPEP | |
| SCHEMBL496172 | 0.91 | BCHE (0.61) | BCHEDNM1OPRD1OPRK1ANPEP | |
| SCHEMBL7951036 | 0.91 | BCHE (0.61) | BCHEDNM1OPRD1OPRK1ANPEP | |
| SCHEMBL2605624 | 0.91 | BCHE (0.61) | BCHEDNM1OPRD1OPRK1ANPEP | |
| Hydrochloric Acid SCHEMBL497150 | 0.90 | BCHE (0.60) | BCHEDNM1OPRD1OPRK1ANPEP | |
| Hydrochloric Acid SCHEMBL5225060 | 0.90 | BCHE (0.60) | BCHEDNM1OPRD1OPRK1ANPEP | |
| SCHEMBL3349419 | 0.87 | BCHE (0.49) | BCHEDNM1OPRD1OPRK1ANPEP | |
| SCHEMBL3348102 | 0.86 | ANPEP (0.48) | BCHESLC6A4ANPEPLMNA | |
| SCHEMBL6890169 | 0.86 | ANPEP (0.48) | BCHESLC6A4ANPEPLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |