Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.43 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3348102 | 1.00 | ANPEP (0.48) | ANPEPERAP2MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5220285 | 0.99 | ANPEP (0.47) | ANPEPERAP2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4044665 | 0.92 | ANPEP (0.55) | ANPEPERAP2SMN1; SMN2MAPTADRB2 | |
| SCHEMBL3347864 | 0.92 | ANPEP (0.55) | ANPEPERAP2SMN1; SMN2MAPTADRB2 | |
| SCHEMBL496056 | 0.92 | ANPEP (0.55) | ANPEPERAP2SMN1; SMN2MAPTADRB2 | |
| SCHEMBL4696783 | 0.92 | ANPEP (0.55) | ANPEPERAP2SMN1; SMN2MAPTADRB2 | |
| Hydrochloric Acid SCHEMBL496686 | 0.90 | ANPEP (0.54) | ANPEPERAP2MAPTADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL5219517 | 0.90 | ANPEP (0.54) | ANPEPERAP2MAPTADRB2ADRB1 | |
| SCHEMBL3351268 | 0.87 | ALDH1A1 (0.47) | ANPEPERAP2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3348066 | 0.86 | KDM4E (0.51) | ANPEPERAP2KMT2AADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |