Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3348729 | 1.00 | CYP1A2 (0.55) | CYP1A2ALDH1A1CYP2C19KMT2AHRH3 | |
| SCHEMBL3350826 | 0.87 | KDM4E (0.58) | CYP1A2ALDH1A1KMT2AKDM4EALOX15 | |
| SCHEMBL4044665 | 0.83 | ANPEP (0.55) | CYP1A2ALDH1A1CYP2C19LMNACYP2D6 | |
| SCHEMBL4696783 | 0.83 | ANPEP (0.55) | CYP1A2ALDH1A1CYP2C19LMNACYP2D6 | |
| SCHEMBL3347864 | 0.83 | ANPEP (0.55) | CYP1A2ALDH1A1CYP2C19LMNACYP2D6 | |
| SCHEMBL496056 | 0.83 | ANPEP (0.55) | CYP1A2ALDH1A1CYP2C19LMNACYP2D6 | |
| Hydrochloric Acid SCHEMBL5219517 | 0.82 | ANPEP (0.54) | MAPTF2 | |
| Hydrochloric Acid SCHEMBL496686 | 0.82 | ANPEP (0.54) | MAPTF2 | |
| SCHEMBL4038793 | 0.82 | ANPEP (0.48) | KMT2ALMNASMN1; SMN2TDP1F2 | |
| SCHEMBL5438930 | 0.81 | KMT2A (0.51) | CYP1A2ALDH1A1CYP2C19KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |