Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 5/20 | 0.53 |
| ▸ | METAP1 | P53582 | 5/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CASR | P41180 | 3/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3351722 | 1.00 | METAP2 (0.53) | METAP2METAP1BCHECASREPHX2 | |
| SCHEMBL3354050 | 1.00 | METAP2 (0.53) | METAP2METAP1BCHECASREPHX2 | |
| SCHEMBL7612959 | 0.81 | METAP2 (0.49) | METAP2METAP1BCHEEPHX2ACP3 | |
| SCHEMBL7612965 | 0.81 | METAP2 (0.49) | METAP2METAP1BCHEEPHX2ACP3 | |
| SCHEMBL7610434 | 0.81 | METAP2 (0.47) | METAP2METAP1BCHECASREPHX2 | |
| SCHEMBL7610441 | 0.81 | METAP2 (0.47) | METAP2METAP1BCHECASREPHX2 | |
| SCHEMBL7610450 | 0.81 | METAP2 (0.47) | METAP2METAP1BCHECASREPHX2 | |
| SCHEMBL3352220 | 0.80 | BCHE (0.70) | BCHEF2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3347420 | 0.80 | BCHE (0.70) | BCHEF2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3350343 | 0.80 | BCHE (0.70) | BCHEF2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |