Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | IDO1 | P14902 | 1/20 | 0.59 |
| ▸ | NOS1 | P29475 | 2/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | VHL | P40337 | 1/20 | 0.39 |
| ▸ | ELOC | Q15369 | 1/20 | 0.39 |
| ▸ | ELOB | Q15370 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL41775 | 0.78 | TSHR (0.67) | NOS1TSHRPRSS1PRSS2PRSS3 | |
| SCHEMBL17065246 | 0.78 | THRB (0.59) | THRBIDO1NOS1NOS2CA1 | |
| SCHEMBL131948 | 0.76 | IDO1 (0.56) | THRBIDO1NOS1NOS2CA1 | |
| SCHEMBL15004592 | 0.76 | KDM4E (0.54) | NOS1NOS2TSHRPRSS1PRSS2 | |
| SCHEMBL6979704 | 0.76 | IDO1 (0.56) | THRBIDO1NOS1NOS2MEN1 | |
| Hydrochloric Acid SCHEMBL17065240 | 0.76 | THRB (0.56) | THRBIDO1NOS1NOS2CA1 | |
| SCHEMBL1505831 | 0.76 | MEN1 (0.58) | THRBIDO1NOS1NOS2HDAC1 | |
| SCHEMBL7754741 | 0.76 | THRB (0.56) | THRBIDO1NOS1NOS2MEN1 | |
| SCHEMBL12976226 | 0.76 | THRB (0.56) | THRBIDO1NOS1NOS2TSHR | |
| SCHEMBL4941612 | 0.76 | THRB (0.56) | THRBIDO1NOS1NOS2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110729-A1 | Primary N-hydroxylamines | NIH | 2004-06-10 | — | — | US | claimed |
| US-6455589-B1 | AN ORALLY ADMINISTRABLE EFFECTIVE UNIT SOLID DOSAGE OF A PRIMARY N-HYDROXYLAMINE OR A SALT, FREE OF NITRONE; USEFUL FOR REDUCING OXIDATIVE DAMAGE OR DELAYING SENESCENCE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-09-24 | — | — | US | claimed |
| WO-2001030979-A1 | PRIMARY N-HYDROXYLAMINES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-05-03 | — | — | WO | claimed |
| WO-2001030979-A1 | PRIMARY N-HYDROXYLAMINES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-05-03 | — | — | WO | disclosed |
| US-5660974-A | EXPOSING, DEVELOPING | EASTMAN KODAK COMPANY (US) | 1997-08-26 | — | — | US | disclosed |