Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL420551 | 0.88 | ALDH1A1 (0.38) | CYP3A4CYP2C9CYP2C19GAAPOLB | |
| SCHEMBL5892273 | 0.86 | CYP3A4 (0.40) | CYP3A4CYP2C9CYP2C19GAAPOLB | |
| SCHEMBL5892255 | 0.83 | GAA (0.39) | CYP3A4CYP2C9CYP2C19GAAPOLB | |
| SCHEMBL13203905 | 0.83 | CYP3A4 (0.38) | CYP3A4CYP2C9CYP2C19GAAPOLB | |
| SCHEMBL2990006 | 0.82 | CYP3A4 (0.39) | CYP3A4CYP2C9CYP2C19GAAPOLB | |
| SCHEMBL3633847 | 0.82 | POLB (0.42) | CYP3A4CYP2C9CYP2C19GAAPOLB | |
| SCHEMBL26089024 | 0.80 | CYP3A4 (0.36) | CYP3A4CYP2C9CYP2C19GAAPOLB | |
| SCHEMBL19379182 | 0.80 | CYP3A4 (0.36) | CYP3A4CYP2C9CYP2C19GAAPOLB | |
| SCHEMBL4087214 | 0.79 | SMN1; SMN2 (0.37) | CYP2C19CA12CA1CA2CA9 | |
| SCHEMBL14822032 | 0.78 | HTT (0.37) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10103401-B2 | Polymer electrolyte composition and polymer electrolyte membrane, polymer electrolyte membrane with catalyst layer, membrane electrode assembly, and polymer electrolyte fuel cell each using the same | TORAY INDUSTRIES, INC. (JP) | 2018-10-16 | — | — | US | disclosed |
| EP-3131145-B1 | POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTROLYTE ASSEMBLY, AND SOLID POLYMER FUEL CELL USING SAME | TORAY INDUSTRIES (JP) | 2018-09-05 | — | — | EP | disclosed |
| US-9827257-B2 | Antitumoral compounds | PHARMA MAR, S.A. (ES) | 2017-11-28 | — | — | US | disclosed |
| US-9750759-B2 | Antitumoral compounds | PHARMA MAR, S.A. (ES) | 2017-09-05 | — | — | US | disclosed |
| US-20170125832-A1 | POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, POLYMER ELECTROLYTE MEMBRANE WITH CATALYST LAYER, MEMBRANE ELECTRODE ASSEMBLY, AND POLYMER ELECTROLYTE FUEL CELL EACH USING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2017-05-04 | — | — | US | disclosed |
| EP-3131145-A1 | POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTROLYTE ASSEMBLY, AND SOLID POLYMER FUEL CELL USING SAME | Toray Industries, Inc. (JP) | 2017-02-15 | — | — | EP | disclosed |
| EP-2597091-B1 | Antitumoral Compounds | PHARMA MAR SA (ES) | 2016-04-20 | — | — | EP | disclosed |
| US-20150344454-A1 | ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A. (ES) | 2015-12-03 | — | — | US | disclosed |
| US-20150342972-A1 | ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A. (ES) | 2015-12-03 | — | — | US | disclosed |
| US-9187445-B2 | Antitumoral compounds | PHARMA MAR, S.A. (ES) | 2015-11-17 | — | — | US | disclosed |
| US-7365207-B2 | Process for the production of chiral propionic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 2008-04-29 | — | — | US | disclosed |
| WO-2007144423-A1 | ANTITUMORAL DIHYDROPYRAN-2-ONE COMPOUNDS | PHARMA MAR, S.A. (ES) | 2007-12-21 | — | — | WO | disclosed |
| EP-1670792-B1 | PROCESS FOR THE PREPARATION OF CHIRAL PROPIONIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2007-12-19 | — | — | EP | disclosed |
| US-20070249842-A1 | Process for the production of chiral propionic acid derivatives | PUENTENER KURT | 2007-10-25 | — | — | US | disclosed |
| US-20070249842-A1 | Process for the production of chiral propionic acid derivatives | PUENTENER KURT | 2007-10-25 | — | — | US | disclosed |
| US-7262303-B2 | Process for the production of chiral propionic acid derivatives | HOFFMAN-LA ROCHE INC. (US) | 2007-08-28 | — | — | US | disclosed |
| US-7262303-B2 | Process for the production of chiral propionic acid derivatives | HOFFMAN-LA ROCHE INC. (US) | 2007-08-28 | — | — | US | disclosed |
| EP-1670792-A1 | PROCESS FOR THE PREPARATION OF CHIRAL PROPIONIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005030764-A1 | PROCESS FOR THE PREPARATION OF CHIRAL PROPIONIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-04-07 | — | — | WO | disclosed |
| US-20050070714-A1 | Process for the production of chiral propionic acid derivatives | HOFFMANN-LA ROCHE INC. | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344454-A1 | ANTITUMORAL COMPOUNDS | TP53, CCNY, RB1 | CYP3A4 1645/4885CYP2C9 2327/4885CYP2C19 2097/4885 |
| US-20150342972-A1 | ANTITUMORAL COMPOUNDS | TP53, CCNY, RB1 | CYP3A4 1645/4885CYP2C9 2327/4885CYP2C19 2097/4885 |
| US-20050070714-A1 | Process for the production of chiral propionic acid derivatives | HRH4, HRH3, HRH1 | CYP3A4 22/4885CYP2C9 86/4885CYP2C19 144/4885 |
| US-20070249842-A1 | Process for the production of chiral propionic acid derivatives | HRH4, HRH3, HRH1 | CYP3A4 22/4885CYP2C9 86/4885CYP2C19 144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.