Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888255 | 0.85 | KDM4E (0.38) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL6887442 | 0.85 | KDM4E (0.38) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL6886809 | 0.80 | KDM4E (0.39) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL7734526 | 0.78 | ESR1 (0.33) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL6895255 | 0.77 | KDM4E (0.40) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL6890980 | 0.75 | KDM4E (0.37) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL6893546 | 0.74 | CACNA1C (0.35) | ESR1PTGS1 | |
| SCHEMBL6886821 | 0.74 | CACNA1C (0.35) | ESR1PTGS1 | |
| SCHEMBL6893817 | 0.74 | CACNA1C (0.35) | ESR1PTGS1 | |
| SCHEMBL6887231 | 0.74 | CACNA1C (0.35) | ESR1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677331-B2 | HAVING SUBSTITUTED IMIDAZO(5,1-B)THIAZOLE GROUP AT 2-POSITION; MICROBIOCIDES AGAINST BETA-LACTAMASE PRODUCING BACTERIA AND RESISTANT PSEUDOMONAS | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-01-13 | — | — | US | disclosed |