Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.60 |
| ▸ | APAF1 | O14727 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | RAD52 | P43351 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.47 |
| ▸ | LSS | P48449 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | APEX1 | P27695 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3005224 | 1.00 | DNM1 (0.60) | DNM1APAF1HSP90AA1RAD52RECQL | |
| SCHEMBL1040145 | 1.00 | DNM1 (0.60) | DNM1APAF1HSP90AA1RAD52RECQL | |
| SCHEMBL68320 | 1.00 | DNM1 (0.60) | DNM1APAF1HSP90AA1RAD52RECQL | |
| SCHEMBL548835 | 1.00 | DNM1 (0.60) | DNM1APAF1HSP90AA1RAD52RECQL | |
| Cetrimonium SCHEMBL237554 | 1.00 | DNM1 (0.60) | DNM1APAF1HSP90AA1RAD52RECQL | |
| SCHEMBL25414052 | 1.00 | DNM1 (0.60) | DNM1APAF1HSP90AA1RAD52RECQL | |
| SCHEMBL126381 | 1.00 | DNM1 (0.60) | DNM1APAF1HSP90AA1RAD52RECQL | |
| SCHEMBL238047 | 1.00 | DNM1 (0.60) | DNM1APAF1HSP90AA1RAD52RECQL | |
| SCHEMBL6681513 | 1.00 | DNM1 (0.60) | DNM1APAF1HSP90AA1RAD52RECQL | |
| Hydrochloric Acid SCHEMBL18192375 | 0.98 | DNM1 (0.61) | DNM1APAF1HSP90AA1RAD52RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0953605-B1 | Flow improved polycarbonate composition | TEIJIN LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| EP-0640646-B1 | Process for production of stabilized polycarnonate | TEIJIN LTD (JP) | 2002-11-06 | — | — | EP | disclosed |
| EP-1221459-A1 | A stabilized polycarbonate | TEIJIN LIMITED (JP) | 2002-07-10 | — | — | EP | disclosed |
| US-6103856-A | LINEAR AROMATIC POLYCARBONATE WHICH HAS BEEN PREPARED BY REACTING AN AROMATIC DIHYDROXY COMPOUND WITH A CARBONATE PRECURSOR THROUGH SOLUTION OR MELT POLYCONDENSATION AND CYCLIC AROMATIC CARBONATE | TEIJIN LIMITED (JP) | 2000-08-15 | — | — | US | disclosed |
| EP-0953605-A2 | Flow improved polycarbonate composition | TEIJIN LIMITED (JP) | 1999-11-03 | — | — | EP | disclosed |
| US-5668202-A | ADDING ORGANOSULFONATE OR SULFATE STABILIZER AFTER MELT POLYCONDENSATION | TEIJIN LIMITED (JP) | 1997-09-16 | — | — | US | disclosed |
| US-5494952-A | CATALYTIC MELT CONDENSATION OF AROMATIC DIHYDROXY COMPOUND AND A CARBONIC ACID DIESTER UNTIL DESIRED VISCOSITY IS REACHED, THEN MIXING WITH STABILIZER CONTAINING QUATERNARY AMMONIUM OR PHOSPHONIUM SALTS OF ORGANIC SULFONIC ACIDS | TEIJIN LIMITED (JP) | 1996-02-27 | — | — | US | disclosed |
| US-5486555-A | Process for production of stabilized polycarbonate | TEIJIN LIMITED (JP) | 1996-01-23 | — | — | US | disclosed |
| EP-0640646-A1 | Process for production of stabilized polycarnonate | TEIJIN LIMITED (JP) | 1995-03-01 | — | — | EP | disclosed |
| EP-0285972-B1 | PROCESS FOR THE PREPARATION OF 2,4-DIAMINOBENZENESULFONIC ACID | BASF Aktiengesellschaft (DE) | 1993-08-11 | — | — | EP | disclosed |
| EP-0285972-A2 | Process for the preparation of 2,4-diaminobenzenesulfonic acid | BASF Aktiengesellschaft (DE) | 1988-10-12 | — | — | EP | disclosed |