Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 9/20 | 0.41 |
| ▸ | CYP21A2 | P08686 | 7/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.41 |
| ▸ | F10 | P00742 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6895530 | 1.00 | LSS (0.44) | LSSCYP17A1CYP21A2CYP11B1F10 | |
| Hydrochloric Acid SCHEMBL6887407 | 0.99 | LSS (0.43) | LSSCYP17A1CYP21A2CYP11B1F10 | |
| Hydrochloric Acid SCHEMBL6887403 | 0.99 | LSS (0.43) | LSSCYP17A1CYP21A2CYP11B1F10 | |
| SCHEMBL6886617 | 0.91 | LSS (0.42) | LSSCYP17A1CYP21A2CYP11B1F10 | |
| SCHEMBL6886612 | 0.91 | LSS (0.42) | LSSCYP17A1CYP21A2CYP11B1F10 | |
| Hydrochloric Acid SCHEMBL6894262 | 0.90 | LSS (0.41) | LSSCYP17A1CYP21A2CYP11B1F10 | |
| Hydrochloric Acid SCHEMBL6894272 | 0.90 | LSS (0.41) | LSSCYP17A1CYP21A2CYP11B1F10 | |
| SCHEMBL6891060 | 0.89 | LSS (0.43) | LSSCYP17A1CYP21A2CYP11B1F10 | |
| Hydrochloric Acid SCHEMBL6893656 | 0.88 | LSS (0.43) | LSSCYP17A1CYP21A2CYP11B1F10 | |
| SCHEMBL6887379 | 0.87 | LSS (0.45) | LSSF10CYP3A4CHRM1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6680312-B2 | FOR THERAPY OF CARDIAC INFARCTION, CEREBRAL THROMBOSIS; INHIBIT ACTIVATED COAGULATION FACTOR X (FXA) TO SHOW ANTI-COAGULANT ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-01-20 | — | — | US | disclosed |
| US-20020193382-A1 | Sulfonamide derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY, LIMITED (JP) | 2002-12-19 | — | — | US | disclosed |
| US-6403595-B1 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-06-11 | — | — | US | disclosed |
| EP-1054005-A1 | SULFONAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND UTILIZATION THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193382-A1 | Sulfonamide derivatives, their production and use | F12, F11, F2 | LSS 1250/4885CYP17A1 575/4885CYP21A2 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.