SCHEMBL6895546

SCHEMBL6895546

CC(=COC=C(C)CCCCO)CCCCO

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SQLE Q14534 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.33
GPR84 Q9NQS5 1/20 0.33
FFAR1 O14842 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
KDM4E B2RXH2 1/20 0.32
LMNA P02545 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1977766 0.78 CES1 (0.42) GPR84FFAR1FFAR4ALDH1A1HSD17B10
SCHEMBL1974603 0.78 CES1 (0.42) GPR84FFAR1FFAR4ALDH1A1HSD17B10
SCHEMBL11382383 0.76
SCHEMBL466624 0.76
1,4-Butanediol SCHEMBL4365143 0.76 SMN1; SMN2 (0.38) SQLESMN1; SMN2LMNAALDH1A1HSD17B10
SCHEMBL466623 0.76
SCHEMBL4374917 0.74 LMNA (0.41) SQLESMN1; SMN2GPR84FFAR1FFAR4
1,6-Hexanediol SCHEMBL4371375 0.74 LMNA (0.41) SQLESMN1; SMN2GPR84FFAR1FFAR4
SCHEMBL13957444 0.74 SQLE (0.50) SQLESMN1; SMN2GPR84FFAR1FFAR4
SCHEMBL4371580 0.74 LMNA (0.41) SQLESMN1; SMN2GPR84FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5698655-A REACTING AN ORGANOSILICON COMPOUND, AN OXYALKYLENE CONTAINING COMPOUND AND A CATALYST DOW CORNING CORPORATION (US) 1997-12-16 US claimed
US-5625023-A REACTION PRODUCT OF ORGANOSILICON COMPOUND, OXYALKYLENE COMPOUND, CATALYST DOW CORNING CORPORATION (US) 1997-04-29 US claimed
US-6805914-B2 COMPRISING A SOLVENTLESS SILICONE COATING COMPOSITION AND A LIQUID SILICONE MIST SUPPRESSANT COMPOSITION OBTAINED BY A METHOD COMPRISING REACTING A LARGE EXCESS OF AT LEAST ONE ORGANOHYDROGENSILICON COMPOUND CONTAINING AT LEAST THREE DOW CORNING CORPORATION 2004-10-19 US disclosed
EP-1294819-B1 SILICONE COATING CONTAINING SILICONE MIST SUPPRESSANT COMPOSITIONS DOW CORNING (US) 2004-10-06 EP disclosed
US-20030120000-A1 Silicone coatings containing silicone mist suppressant compositions DOW SILICONES CORPORATION 2003-06-26 US disclosed
EP-1294819-A2 SILICONE COATING CONTAINING SILICONE MIST SUPPRESSANT COMPOSITIONS Dow Corning Corporation (US) 2003-03-26 EP disclosed
US-6489407-B1 SOLVENT-FREE (CO-)POLYSILOXANES USED AS ANTISTICK AGENTS FOR LAMINATION OF PAPER SUBSTRATES DOW CORNING CORPORATION 2002-12-03 US disclosed
WO-2001098418-A2 SILICONE COATINGS CONTAINING SILICONE MIST SUPPRESSANT COMPOSITIONS DOW CORNING CORPORATION (US) 2001-12-27 WO disclosed
US-5994454-A REACTING AN ORGANOSILICON COMPOUND, AN OXYALKYLENE CONTAINING COMPOUND, AND A CATALYST. THE COMPOSITION, WHEN ADDED TO CURABLE SILICONE COATINGS, REDUCES THE AMOUNT OF SILICONE MIST IN HIGH SPEED COATING PROCESSES. DOW CORNING CORPORATION (US) 1999-11-30 US disclosed
EP-0716115-B1 Aerosol suppressant compositions for silicone coatings DOW CORNING (US) 1999-06-02 EP disclosed
US-5698655-A REACTING AN ORGANOSILICON COMPOUND, AN OXYALKYLENE CONTAINING COMPOUND AND A CATALYST DOW CORNING CORPORATION (US) 1997-12-16 US disclosed
US-5625023-A REACTION PRODUCT OF ORGANOSILICON COMPOUND, OXYALKYLENE COMPOUND, CATALYST DOW CORNING CORPORATION (US) 1997-04-29 US disclosed
EP-0542484-B1 Organosilicon compounds and compositions containing them DOW CORNING (GB) 1997-01-02 EP disclosed
EP-0716115-A2 Aerosol suppressant compositions for silicone coatings DOW CORNING CORPORATION (US) 1996-06-12 EP disclosed
US-5331020-A Organosilicon compounds and compositions containing them DOW CORNING LIMITED (GB) 1994-07-19 US disclosed
US-5270423-A Organosilicon compounds and compositions containing them DOW CORNING LIMITED (GB) 1993-12-14 US disclosed
EP-0542484-A1 Organosilicon compounds and compositions containing them Dow Corning Limited (GB) 1993-05-19 EP disclosed