⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5993559 | 0.80 | LMNA (0.43) | — | |
| SCHEMBL2040423 | 0.74 | — | — | |
| SCHEMBL6740266 | 0.74 | — | — | |
| SCHEMBL14489602 | 0.74 | — | — | |
| SCHEMBL9706230 | 0.72 | — | — | |
| SCHEMBL1457168 | 0.72 | — | — | |
| SCHEMBL27603964 | 0.72 | — | — | |
| SCHEMBL25332582 | 0.70 | — | — | |
| SCHEMBL13066201 | 0.70 | — | — | |
| SCHEMBL2042195 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103930213-B | Mineral processing using polymeric materials including moieties that selectively bind to minerals | 喜德矿物加工有限公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-103562208-B | tricyclic gyrase inhibitors | 默沙东公司 | 2016-08-31 | — | — | CN | disclosed |
| CN-102596954-B | JAK2 inhibitor and be used for the treatment of the purposes of myeloproliferative disease and cancer | BRISTOL-MYERS SQUIBB CO. (US) | 2015-12-16 | — | — | CN | disclosed |
| CN-103930213-A | Mineral processing using polymeric materials including moieties that selectively bind to minerals | NOVEL POLYMER SOLUTIONS LTD | 2014-07-16 | — | — | CN | disclosed |
| CN-103562208-A | Tricyclic gyrase inhibitors | TRIUS THERAPEUTICS INC | 2014-02-05 | — | — | CN | disclosed |
| CN-102596954-A | JAK2 inhibitors and their use for the treatment of myeloproliferative diseases and cancer | BRISTOL MYERS SQUIBB CO | 2012-07-18 | — | — | CN | disclosed |
| CN-102300862-A | Compounds useful as inhibitors of ATR kinase | — | 2011-12-28 | — | — | CN | disclosed |
| US-20100298381-A1 | GAMMA SECRETASE MODULATORS | SCHERING CORPORATION | 2010-11-25 | — | — | US | disclosed |
| CN-100490683-C | Products containing isothiocyanate preservative systems and methods of use | PROCTER & GAMBLE (US) | 2009-05-27 | — | — | CN | disclosed |
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | disclosed |
| CN-1391446-A | Products comprising isothiocyanate preservative system and methods of their use | PROCTER & GAMBLE (US) | 2003-01-15 | — | — | CN | disclosed |
| EP-1189891-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-03-27 | — | — | EP | disclosed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | disclosed |
| EP-1150565-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION bioscience AG (DE) | 2001-11-07 | — | — | EP | disclosed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | disclosed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | disclosed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | disclosed |