Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL730130 | 0.93 | ALDH1A1 (0.48) | ALDH1A1SOAT1TSHRCYP3A4ATM | |
| SCHEMBL12646309 | 0.84 | CYP3A4 (0.64) | ALDH1A1TSHRCYP3A4ATMTDP1 | |
| SCHEMBL30690962 | 0.84 | ALDH1A1 (0.40) | ALDH1A1SOAT1TSHRCYP3A4ATM | |
| SCHEMBL11653544 | 0.83 | TSHR (0.42) | ALDH1A1SOAT1TSHRCYP3A4ATM | |
| SCHEMBL4922810 | 0.83 | TSHR (0.42) | ALDH1A1SOAT1TSHRCYP3A4ATM | |
| SCHEMBL5965019 | 0.82 | TSHR (0.39) | ALDH1A1SOAT1TSHRCYP3A4ATM | |
| SCHEMBL5965021 | 0.82 | TSHR (0.39) | ALDH1A1SOAT1TSHRCYP3A4ATM | |
| SCHEMBL11750627 | 0.81 | ALDH1A1 (0.42) | ALDH1A1SOAT1TSHRCYP3A4ATM | |
| SCHEMBL5724509 | 0.79 | ALDH1A1 (0.59) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL8961057 | 0.79 | ALDH1A1 (0.59) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677331-B2 | HAVING SUBSTITUTED IMIDAZO(5,1-B)THIAZOLE GROUP AT 2-POSITION; MICROBIOCIDES AGAINST BETA-LACTAMASE PRODUCING BACTERIA AND RESISTANT PSEUDOMONAS | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-01-13 | — | — | US | disclosed |