Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6896286 | 1.00 | ACE (0.41) | ACETACR1 | |
| SCHEMBL8829874 | 1.00 | ACE (0.41) | ACETACR1 | |
| SCHEMBL6895208 | 0.83 | CCKBR (0.53) | — | |
| SCHEMBL9309283 | 0.82 | TACR1 (0.38) | ACETACR1 | |
| SCHEMBL27312036 | 0.79 | TACR1 (0.57) | TACR1 | |
| SCHEMBL8903230 | 0.79 | TACR1 (0.57) | TACR1 | |
| SCHEMBL8829824 | 0.79 | TACR1 (0.57) | TACR1 | |
| SCHEMBL19022496 | 0.79 | ECE1 (0.46) | TACR1 | |
| SCHEMBL19022497 | 0.79 | ECE1 (0.46) | TACR1 | |
| SCHEMBL6897076 | 0.77 | CCKBR (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405537-B1 | N-substituted cycloalkyl and polycycloalkyl alpha-substituted Trp-Phe- and phenethylamine derivatives | WARNER LAMBERT CO (US) | 2004-09-08 | — | — | EP | disclosed |
| US-5631281-A | COMPOUNDS FOR TREATMENT OF ANXIETY WITH INDOLE AMIDES | WARNER-LAMBERT COMPANY (US) | 1997-05-20 | — | — | US | disclosed |
| US-5622983-A | ANTIOBESITY AGENTS, ANTIPSYCHOTIC AGENTS, ANTIULCER AGENTS | WARNER-LAMBERT COMPANY (US) | 1997-04-22 | — | — | US | disclosed |
| US-5580896-A | Treatment of pain and colorectal cancer with dipeptoids of α-substituted Trp-Phe derivatives | WARNER-LAMBERT COMPANY (US) | 1996-12-03 | — | — | US | disclosed |
| EP-0479910-A1 | N-SUBSTITUTED CYCLOALKYL AND POLYCYCLOALKYL ALPHA-SUBSTITUTED Trp-Phe- AND PHENETHYLAMINE DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1992-04-15 | — | — | EP | disclosed |
| WO-1991000274-A1 | N-SUBSTITUTED CYCLOALKYL AND POLYCYCLOALKYL ALPHA-SUBSTITUTED TRP-PHE- AND PHENETHYLAMINE DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1991-01-10 | — | — | WO | disclosed |