Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.51 |
| ▸ | BACE1 | P56817 | 6/20 | 0.50 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608508 | 1.00 | BCHE (0.51) | BCHEBACE1SLC6A11 | |
| SCHEMBL7608509 | 1.00 | BCHE (0.51) | BCHEBACE1SLC6A11 | |
| SCHEMBL5444827 | 0.88 | MMP2 (0.56) | BACE1 | |
| SCHEMBL5444816 | 0.88 | MMP2 (0.56) | BACE1 | |
| SCHEMBL7606956 | 0.86 | BACE1 (0.51) | BCHEBACE1SLC6A11 | |
| SCHEMBL7606952 | 0.86 | BACE1 (0.51) | BCHEBACE1SLC6A11 | |
| SCHEMBL7610959 | 0.83 | CYP3A4 (0.49) | BCHEBACE1SLC6A11 | |
| SCHEMBL27592784 | 0.83 | CYP3A4 (0.49) | BCHEBACE1SLC6A11 | |
| SCHEMBL7610965 | 0.83 | CYP3A4 (0.49) | BCHEBACE1SLC6A11 | |
| SCHEMBL5444846 | 0.82 | BCHE (0.71) | BCHEBACE1SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |