Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | CA9 | Q16790 | 3/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA3 | P07451 | 2/20 | 0.61 |
| ▸ | CA4 | P22748 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 6/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | BAX | Q07812 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroquinone SCHEMBL28744368 | 0.88 | CA3 (0.50) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL11119394 | 0.88 | CA12 (0.69) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL27629000 | 0.87 | CA12 (0.46) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL27981066 | 0.86 | CA12 (0.65) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL2209460 | 0.86 | CA12 (0.65) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL6908600 | 0.86 | CA12 (0.65) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL27981079 | 0.86 | CA12 (0.65) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL28637371 | 0.83 | TDP1 (0.61) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL6907309 | 0.83 | TDP1 (0.61) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL28498144 | 0.83 | TDP1 (0.61) | CA12CA2CA9CA14CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108164397-B | Catechol derivative and its preparation method | 暨南大学 | 2020-11-13 | — | — | CN | claimed |
| CN-103387547-B | A kind of method preparing phonetic mite amine | SHENYANG SINOCHEM PESTICIDE CHEMICAL RESEARCH AND DEVELOPMENT CO., LTD. (CN) | 2016-03-23 | — | — | CN | claimed |
| CN-103387546-B | One prepares the method for 2-(2,4 dichloro benzene amido)-6-trifluoromethyl pyrimidine phenol | SINOCHEM CORPORATION (CN) | 2015-08-19 | — | — | CN | claimed |
| CN-103387547-A | Pyriminostrobin preparation method | SINOCHEM CORP | 2013-11-13 | — | — | CN | claimed |
| CN-103387546-A | Method for preparing 2-(2,4-dichloroanilino)-6-trifluoromethylpyrimidylphenol | SINOCHEM CORP | 2013-11-13 | — | — | CN | claimed |
| CN-103012289-A | Synthesis and biological activity of cyanoacrylate compound containing pyrimidine phenylate structure | UNIV NANKAI | 2013-04-03 | — | — | CN | claimed |
| CN-102718890-A | Alpha-aminophenylpyridine ether phosphate derivatives and preparation method thereof | INST OCEANOLOGY CHINESE ACAD | 2012-10-10 | — | — | CN | claimed |
| CN-117836278-A | SOS1 inhibitor, preparation method and application thereof | 上海海和药物研究开发股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-116063285-A | Substituted pyrimidine (thio) ester compound and application thereof | 沈阳中化农药化工研发有限公司 | 2023-05-05 | — | — | CN | disclosed |
| WO-2023029833-A1 | SOS1 INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海海和药物研究开发股份有限公司 | 2023-03-09 | — | — | WO | disclosed |
| CN-109743875-B | Inhibitors of the MENIN-MLL interaction | 生命医药有限责任公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-110663693-A | Pesticide composition, pesticide preparation and application of pesticide composition and pesticide preparation | 沈阳中化农药化工研发有限公司 | 2020-01-10 | — | — | CN | disclosed |
| CN-105777717-B | Pyrazolyl pyrimidines ether compound and purposes | 沈阳中化农药化工研发有限公司 | 2019-07-26 | — | — | CN | disclosed |
| WO-2000031003-A1 | PROCESS FOR CONVERTING AN ALCOHOL TO THE CORRESPONDING FLUORIDE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-06-02 | — | — | WO | disclosed |
| CN-1039781-C | Antiscolic compound pharmaceutical | INST OF PREVENTION AND TREATME (CN) | 1998-09-16 | — | — | CN | disclosed |
| US-5380460-A | Ferroelectric liquid crystal compounds containing chiral haloalkoxy tail units and compositions containing them | DISPLAYTECH, INC. (US) | 1995-01-10 | — | — | US | disclosed |
| WO-1993006192-A1 | FERROELECTRIC LIQUID CRYSTAL COMPOUNDS CONTAINING CHIRAL HALOALKOXY TAIL UNITS AND COMPOSITIONS CONTAINING THEM | DISPLAYTECH, INCORPORATED (US) | 1993-04-01 | — | — | WO | disclosed |
| US-5178793-A | Chiral epoxy ethers with phenyl and pyridine or pyrimidine ring | UNIVERSITY RESEARCH CORPORATION (US) | 1993-01-12 | — | — | US | disclosed |
| US-5051506-A | Compounds for electrooptical displays | DISPLAYTECH, INC. (US) | 1991-09-24 | — | — | US | disclosed |
| US-RE30199-E | Oxidation hair dyes based upon tetraaminopyrimidine developers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 1980-01-29 | — | — | US | disclosed |