Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27285153 | 1.00 | TSHR (0.46) | TSHRTHRBALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL4526824 | 1.00 | TSHR (0.46) | TSHRTHRBALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL6895529 | 0.97 | TSHR (0.42) | TSHRTHRBALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL6893259 | 0.89 | — | — | |
| Fluoride SCHEMBL27930931 | 0.86 | TSHR (0.39) | TSHRTHRBALDH1A1LMNA | |
| SCHEMBL5881449 | 0.77 | — | — | |
| SCHEMBL5968706 | 0.77 | TSHR (0.44) | TSHRTHRBALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL7939368 | 0.77 | TSHR (0.44) | TSHRTHRBALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL8769542 | 0.75 | TSHR (0.42) | TSHRTHRBALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL8995998 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098926-B1 | CROSS-LINKABLE HYPERBRANCHED POLYMERS, METHOD FOR THE PRODUCTION AND USE OF THE SAME | BAYER MATERIALSCIENCE AG (DE) | 2004-03-03 | — | — | EP | disclosed |