Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13025717 | 0.90 | CYP2C9 (0.42) | CYP2C9MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL7907390 | 0.87 | CYP2C9 (0.41) | CYP2C9MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL9457329 | 0.87 | RAB9A (0.39) | CYP2C9MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL9191317 | 0.87 | RAB9A (0.39) | CYP2C9MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL9292192 | 0.86 | KMT2A (0.36) | MAPTKMT2ARAB9AESR2ESR1 | |
| SCHEMBL9491245 | 0.85 | ACACB (0.33) | CYP2C9MAPTALDH1A1LMNAACACB | |
| SCHEMBL12741551 | 0.85 | MAPT (0.34) | CYP2C9MAPTALDH1A1LMNAESR2 | |
| SCHEMBL12737946 | 0.85 | MAPT (0.34) | CYP2C9MAPTALDH1A1LMNAESR2 | |
| SCHEMBL6892105 | 0.84 | CYP2C9 (0.37) | CYP2C9MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL6892100 | 0.84 | CYP2C9 (0.37) | CYP2C9MAPTALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1081123-B1 | 2,3-Difluorophenyl derivative having negative dielectric anisotropy, liquid crystal composition, and liquid crystal display device | CHISSO CORP (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-6548126-B1 | Reduced electric power consumption and decreased leakage of electromagnetic waves | CHISSO CORPORATION (JP) | 2003-04-15 | — | — | US | disclosed |
| EP-1081123-A2 | 2,3-Difluorophenyl derivative having negative dielectric anisotropy, liquid crystal composition, and liquid crystal display device | CHISSO CORPORATION (JP) | 2001-03-07 | — | — | EP | disclosed |