Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.81 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.81 |
| ▸ | GAA | P10253 | 1/20 | 0.81 |
| ▸ | TSHR | P16473 | 1/20 | 0.81 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.81 |
| ▸ | HTT | P42858 | 1/20 | 0.81 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | RORC | P51449 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8173807 | 0.94 | ABCC4 (0.69) | LMNAABCC4GAATSHRPTGS1 | |
| Felbinac SCHEMBL26084 | 0.90 | LMNA (1.00) | LMNAABCC4GAATSHRPTGS1 | |
| Felbinac SCHEMBL28284674 | 0.88 | LMNA (0.95) | LMNAABCC4GAATSHRPTGS1 | |
| Felbinac SCHEMBL28286223 | 0.88 | LMNA (0.95) | LMNAABCC4GAATSHRPTGS1 | |
| Felbinac SCHEMBL28284752 | 0.88 | LMNA (0.95) | LMNAABCC4GAATSHRPTGS1 | |
| Felbinac SCHEMBL28284677 | 0.88 | LMNA (0.95) | LMNAABCC4GAATSHRPTGS1 | |
| Felbinac SCHEMBL8844919 | 0.88 | LMNA (0.95) | LMNAABCC4GAATSHRPTGS1 | |
| Felbinac SCHEMBL28284672 | 0.88 | LMNA (0.95) | LMNAABCC4GAATSHRPTGS1 | |
| Felbinac SCHEMBL384892 | 0.88 | LMNA (0.95) | LMNAABCC4GAATSHRPTGS1 | |
| Felbinac SCHEMBL28286222 | 0.88 | LMNA (0.95) | LMNAABCC4GAATSHRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | disclosed |