⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6033223 | 0.69 | — | — | |
| SCHEMBL8914737 | 0.68 | — | — | |
| SCHEMBL8009050 | 0.65 | — | — | |
| SCHEMBL8009333 | 0.65 | — | — | |
| SCHEMBL7975737 | 0.63 | — | — | |
| SCHEMBL24192307 | 0.62 | TSHR (0.31) | — | |
| SCHEMBL207480 | 0.62 | — | — | |
| SCHEMBL11334417 | 0.61 | — | — | |
| SCHEMBL5729366 | 0.61 | TDP1 (0.39) | — | |
| SCHEMBL21707535 | 0.60 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115650827-B | Preparation method, intermediate compound and synthesis method for anthracycline derivatives | 戊言医药科技（上海）有限公司 | 2024-03-15 | — | — | CN | claimed |
| US-9487494-B2 | Cyclic hydrocarbon compounds for the treatment of diseases | LEO PHARMA A/S (DK) | 2016-11-08 | — | — | US | claimed |
| US-20140088152-A1 | COMPOSITION FOR PREVENTING AND TREATING CARDIOVASCULAR DISEASES, CONTAINING PYRAZOLE DERIVATIVE | EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION (KR) | 2014-03-27 | — | — | US | claimed |
| US-8637674-B2 | Pyrazole derivatives, preparation method thereof, and composition for prevention and treatment of osteoporosis containing same | EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION (KR) | 2014-01-28 | — | — | US | claimed |
| US-20120232117-A1 | PYRAZOLE DERIVATIVES, PREPARATION METHOD THEREOF, AND COMPOSITION FOR PREVENTION AND TREATMENT OF OSTEOPOROSIS CONTAINING SAME | EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION (KR) | 2012-09-13 | — | — | US | claimed |
| EP-1975158-B9 | NOVEL PYRROLE DERIVATIVES WITH HISTONE DEACETYLASE INHIBITOR ACTIVITY | UNIV PAIS VASCO (ES) | 2012-02-29 | — | — | EP | claimed |
| US-20110319293-A1 | SYNTHETIC PROTEASE SUBSTRATES, ASSAY METHODS USING SUCH SUBSTRATES AND KITS FOR PRACTICING THE ASSAY | LIFESENSORS, INC. | 2011-12-29 | — | — | US | claimed |
| EP-1975158-B1 | NOVEL PYRROLE DERIVATIVES WITH HISTONE DEACETYLASE INHIBITOR ACTIVITY | UNIV PAIS VASCO (ES) | 2011-07-13 | — | — | EP | claimed |
| US-20100317582-A1 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2010-12-16 | — | — | US | claimed |
| EP-2234961-A2 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2010-10-06 | — | — | EP | claimed |
| EP-1443046-A1 | NOVEL 4-(2FUROYL)AMINOPIPERIDINES, INTERMEDIATES IN SYNTHESIZING THE SAME, PROCESS FOR PRODUCING THE SAME AND MEDICINAL USE OF THE SAME | Kyorin Pharmaceutical Co., Ltd. (JP) | 2004-08-04 | — | — | EP | claimed |
| EP-0900241-B1 | SILYL LINKER FOR SOLID PHASE ORGANIC SYNTHESIS OF ARYL-CONTAINING MOLECULES | SMITHKLINE BEECHAM CORP (US) | 2004-01-28 | — | — | EP | claimed |
| US-6420417-B1 | TREATMENT OF HYPERLIPIDEMIC CONDITIONS SUCH AS THOSE ASSOCIATED WITH ATHEROSCLEROSIS OR HYPERCHOLESTEROLEMIA IN MAMMALS | G. D. SEARLE & CO. | 2002-07-16 | — | — | US | claimed |
| EP-0734398-B1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2002-02-27 | — | — | EP | claimed |
| US-6268392-B1 | Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors | G. D. SEARLE & CO. | 2001-07-31 | — | — | US | claimed |
| US-6127489-A | Silyl linker for solid phase organic synthesis of aryl-containing molecules | SMITHKLINE BEECHAM CORPORATION (US) | 2000-10-03 | — | — | US | claimed |
| US-5773512-A | Compounds and methods | SMITHKLINE BEECHAM CORP. (US) | 1998-06-30 | — | — | US | claimed |
| EP-0734398-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 1997-04-16 | — | — | EP | claimed |
| EP-0734398-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-10-02 | — | — | EP | claimed |
| WO-1995016712-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-06-22 | — | — | WO | claimed |