SCHEMBL6897145

SCHEMBL6897145

CCCCc1ccc(C(=O)O)c(C(=O)O)c1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BID P55957 6/20 0.44
MCL1 Q07820 6/20 0.44
BCL2L1 Q07817 5/20 0.44
BAK1 Q16611 5/20 0.44
PPARA Q07869 3/20 0.44
KAT8 Q9H7Z6 2/20 0.44
PPARG P37231 2/20 0.44
SAE1 Q9UBE0 2/20 0.44
EP300 Q09472 1/20 0.44
KAT2A Q92830 1/20 0.44
KAT2B Q92831 1/20 0.44
KAT5 Q92993 1/20 0.44
GABRP O00591 2/20 0.41
GABRD O14764 2/20 0.41
GABRA1 P14867 2/20 0.41
GABRB1 P18505 2/20 0.41
GABRG2 P18507 2/20 0.41
GABRB3 P28472 2/20 0.41
GABRA5 P31644 2/20 0.41
GABRA3 P34903 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8674376 0.90 GABRP (0.42) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL28360757 0.88 GABRP (0.43) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL8768035 0.86 DCLRE1A (0.42) KDM4EMAPTALOX15
SCHEMBL28565323 0.85 GABRP (0.41) BIDMCL1BCL2L1BAK1PPARA
Benzene SCHEMBL28926984 0.83 BID (0.54) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL11323683 0.81 RARB (0.49) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL15228013 0.81 BID (0.50) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL30153449 0.81 BID (0.51) BIDMCL1BCL2L1BAK1PPARA
Phthalic Acid SCHEMBL466622 0.79 BID (0.44) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL28382530 0.79 BID (0.48) BIDMCL1BCL2L1BAK1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2361236-B1 METHODS AND APPARATUS FOR CASTING CERAMIC SHEETS CORNING INC (US) 2013-06-05 EP claimed
EP-0750971-B1 Cross-flow honeycomb structure and method of making same CORNING INC (US) 2004-01-21 EP claimed
US-4818626-A Method for producing sintered metalized aluminum nitride ceramic bodies W. C. HERAEUS GMBH (DE) 1989-04-04 US disclosed