Stearic Acid

Stearic Acid

SCHEMBL6897178

CCCCC/C=C\C/C=C\CCCCCCCCC(N)CCCCCCCC/C=C\C/C=C\CCCCC.CCCCCCCCCCCCCCCCCC(=O)O

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 7/20 0.77
PPARD Q03181 6/20 0.77
PPARA Q07869 6/20 0.77
ALDH1A1 P00352 5/20 0.77
F7 P08709 5/20 0.77
F3 P13726 5/20 0.77
FABP4 P15090 4/20 0.77
HSD17B10 Q99714 4/20 0.77
FFAR1 O14842 3/20 0.77
PTGS1 P23219 3/20 0.77
LMNA P02545 3/20 0.77
CYP19A1 P11511 3/20 0.77
ALOX15 P16050 3/20 0.77
NR4A2 P43354 3/20 0.77
KDM4E B2RXH2 2/20 0.77
CYP3A4 P08684 2/20 0.77
HPGD P15428 2/20 0.77
AKR1C3 P42330 2/20 0.77
TDP1 Q9NUW8 2/20 0.77
DUSP3 P51452 2/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oleic Acid SCHEMBL5197583 0.95 PPARG (0.74) PPARGPPARDPPARAALDH1A1F7
Oleic Acid SCHEMBL5197578 0.95 PPARG (0.74) PPARGPPARDPPARAALDH1A1F7
Stearic Acid SCHEMBL5196452 0.95 PPARG (0.74) PPARGPPARDPPARAALDH1A1F7
Oleic Acid SCHEMBL8668601 0.95 PPARG (0.74) PPARGPPARDPPARAALDH1A1F7
Oleic Acid SCHEMBL8668591 0.95 PPARG (0.74) PPARGPPARDPPARAALDH1A1F7
Stearic Acid SCHEMBL5196464 0.95 PPARG (0.74) PPARGPPARDPPARAALDH1A1F7
SCHEMBL6274394 0.94 PPARG (0.72) PPARGPPARDPPARAALDH1A1F7
Linoleic Acid SCHEMBL30685714 0.91 PPARG (0.77) PPARGPPARDPPARAALDH1A1F7
Stearic Acid SCHEMBL5196898 0.91 ALDH1A1 (0.63) PPARGPPARDPPARAALDH1A1F7
SCHEMBL15525144 0.88 FFAR1 (0.72) PPARGPPARDPPARAALDH1A1F7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0704522-B1 Dryer-activated fabric conditioning compositions containing unsaturated fatty acid PROCTER & GAMBLE (US) 2001-11-28 EP claimed
US-6277796-B1 ACETAL COMPOUND THE PROCTER & GAMBLE COMPANY 2001-08-21 US claimed
EP-0712441-B1 DRYER-ACTIVATED FABRIC CONDITIONING COMPOSITIONS CONTAINING ETHOXYLATED/PROPOXYLATED SUGAR DERIVATIVES PROCTER & GAMBLE (US) 1999-10-20 EP claimed
EP-0946699-A1 DRYER-ACTIVATED FABRIC CONDITIONING AND ANTISTATIC COMPOSITIONS WITH IMPROVED PERFUME LONGEVITY THE PROCTER & GAMBLE COMPANY (US) 1999-10-06 EP claimed
EP-0946705-A2 DRYER ADDED FABRIC SOFTENING COMPOSITIONS AND METHOD OF USE FOR THE DELIVERY OF FRAGRANCE DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 1999-10-06 EP claimed
EP-0946700-A1 RINSE-ADDED AND DRYER-ADDED FABRIC SOFTENING COMPOSITIONS AND METHOD OF USE FOR THE DELIVERY OF ESTER FRAGRANCE DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 1999-10-06 EP claimed
US-5962402-A DISCOLORATION INHIBITION OF FABRICS THE PROCTER & GAMBLE COMPANY (US) 1999-10-05 US claimed
US-5929026-A POLYESTER SUBSTRATE HAVING IMPROVED FEEL; USING IN AN AUTOMATIC LAUNDARY DRYER TO CONDITION THE FABRIC THE PROCTER & GAMBLE COMPANY (US) 1999-07-27 US claimed
US-5883069-A POLYESTER NONWOVEN FABRIC WITH SOFTENER THE PROCTER & GAMBLE COMPANY (US) 1999-03-16 US claimed
US-5869443-A CONTAINING MIXTURE OF PHOTOSTABLE ANTIOXIDANT AND SUNSCREEN AGENT THE PROCTER & GAMBLE COMPANY (US) 1999-02-09 US claimed
EP-0704522-A2 Dryer-activated fabric conditioning compositions containing unsaturated fatty acid THE PROCTER & GAMBLE COMPANY (US) 1996-04-03 EP claimed
US-5503756-A ALSO CONTAINING FABRIC SOFTENER CONSISTING OF BIODEGRADABLE QUATERNARY AMMONIUM COMPOUND, ALKOXYLATED SUGAR DERIVATIVE HAVING LONG HYDROPHOBIC GROUP, CARBOXYLIC ACID SALT OF TERTIARY AMINE THE PROCTER & GAMBLE COMPANY (US) 1996-04-02 US claimed
US-5500137-A Fabric softening bar compositions containing fabric softener and enduring perfume THE PROCTER & GAMBLE COMPANY (US) 1996-03-19 US claimed
WO-1996003492-A1 A DRYER-ADDED FABRIC TREATMENT ARTICLE OF MANUFACTURE CONTAINING ANTIOXIDANT AND SUNSCREEN COMPOUNDS FOR SUN-FADE PROTECTION OF FABRICS THE PROCTER & GAMBLE COMPANY (US) 1996-02-08 WO claimed
WO-1996001889-A1 FABRIC SOFTENING BAR COMPOSITIONS CONTAINING FABRIC SOFTENER, NONIONIC PHASE MODIFIER AND WATER THE PROCTER & GAMBLE COMPANY (US) 1996-01-25 WO claimed
US-5476599-A Containing a quaternary ammonium compound and a tertiary amine salt of a carboxylic acid THE PROCTER & GAMBLE COMPANY (US) 1995-12-19 US claimed
WO-1995007342-A1 DRYER-ACTIVATED FABRIC CONDITIONING ARTICLES WITH SOFT POLYESTER SUBSTRATE THE PROCTER & GAMBLE COMPANY (US) 1995-03-16 WO claimed
WO-1995004811-A1 DRYER-ACTIVATED FABRIC CONDITIONING COMPOSITIONS CONTAINING ETHOXYLATED/PROPOXYLATED SUGAR DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 1995-02-16 WO claimed
WO-1995004802-A1 DRYER-ACTIVATED FABRIC CONDITIONING AND ANTISTATIC COMPOSITIONS CONTAINING BIODEGRADABLE COMPOUNDS HAVING UNSATURATION THE PROCTER & GAMBLE COMPANY (US) 1995-02-16 WO claimed
US-5376287-A With carboxylic acid salt of tertiary amine cosoftener; improved antistatic effects THE PROCTER & GAMBLE COMPANY (US) 1994-12-27 US claimed