SCHEMBL689732

SCHEMBL689732

O=Cc1ccc2c(c1)c1cc(C=O)ccc1n2Cc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 4/20 0.55
CYP19A1 P11511 1/20 0.55
P2RX4 Q99571 1/20 0.53
SRC P12931 2/20 0.51
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
LMNA P02545 3/20 0.47
ALDH1A1 P00352 2/20 0.47
NPSR1 Q6W5P4 1/20 0.47
PSMD14 O00487 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
MAPK1 P28482 1/20 0.45
KDM4E B2RXH2 1/20 0.45
MAPT P10636 1/20 0.45
PLA2G2A P14555 2/20 0.42
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30676985 1.00 PTGER4 (0.55) PTGER4CYP19A1P2RX4SRCKMT2A
SCHEMBL689666 0.95 CYP19A1 (0.64) PTGER4CYP19A1P2RX4SRCKMT2A
SCHEMBL96124 0.88 SRC (0.51) PTGER4CYP19A1P2RX4SRCKMT2A
SCHEMBL8156486 0.87 PTGER4 (0.55) PTGER4CYP19A1P2RX4KMT2AMEN1
SCHEMBL28179541 0.85 MAPT (0.56) PTGER4CYP19A1P2RX4KMT2AMEN1
SCHEMBL28392221 0.84 P2RX4 (0.61) PTGER4CYP19A1P2RX4KMT2AMEN1
SCHEMBL4780793 0.84 PTGER4 (0.55) PTGER4CYP19A1P2RX4LMNAPSMD14
SCHEMBL4793959 0.81 PTGER4 (0.55) PTGER4CYP19A1P2RX4SRCKMT2A
SCHEMBL4794184 0.80 PTGER4 (0.54) PTGER4CYP19A1P2RX4LMNAPSMD14
SCHEMBL10977143 0.80 CYP19A1 (0.64) PTGER4CYP19A1P2RX4SRCKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110105812-A A kind of no ink ink-jet ink and its preparation method and application 重庆理工大学 2019-08-09 CN claimed
EP-2107424-B1 Carbazole hole blocking layer photoconductors XEROX CORP (US) 2012-02-29 EP claimed
US-20110006295-A1 COMPOUNDS HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES MERCK PATENT GMBH 2011-01-13 US claimed
EP-2250151-A1 COMPOUNDS HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES Merck Patent GmbH (DE) 2010-11-17 EP claimed
US-7794906-B2 Carbazole hole blocking layer photoconductors XEROX CORPORATION (US) 2010-09-14 US claimed
EP-2107424-A1 Carbazole hole blocking layer photoconductors Xerox Corporation (US) 2009-10-07 EP claimed
US-20090246668-A1 CARBAZOLE HOLE BLOCKING LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-10-01 US claimed
WO-2009112854-A1 COMPOUNDS HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES MERCK PATENT GMBH (DE) 2009-09-17 WO claimed
CN-117229464-A Amphiphilic alternating copolymer, preparation method and application thereof, enzyme complex and preparation method thereof 吉林大学 2023-12-15 CN disclosed
CN-110229333-B Synthetic method of polyimide 湘潭大学 2022-02-15 CN disclosed
CN-107406383-B Compound for lithography, resin, and underlayer film forming material 三菱瓦斯化学株式会社 2021-01-26 CN disclosed
CN-110229333-A A kind of synthetic method of new type polyimide 湘潭大学 2019-09-13 CN disclosed
CN-110105812-A A kind of no ink ink-jet ink and its preparation method and application 重庆理工大学 2019-08-09 CN disclosed
CN-108218867-A A kind of compound, organic electroluminescence device and display device 阜阳欣奕华材料科技有限公司 2018-06-29 CN disclosed
EP-2107424-A1 Carbazole hole blocking layer photoconductors Xerox Corporation (US) 2009-10-07 EP disclosed
US-20090246668-A1 CARBAZOLE HOLE BLOCKING LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-10-01 US disclosed
US-20090246668-A1 CARBAZOLE HOLE BLOCKING LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-10-01 US disclosed
US-20090246668-A1 CARBAZOLE HOLE BLOCKING LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-10-01 US disclosed
WO-2009112854-A1 COMPOUNDS HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES MERCK PATENT GMBH (DE) 2009-09-17 WO disclosed
US-5736284-A HIGH SOLUBILITY IN POLYMER BINDER TAKASAGO INTERNATIONAL CORPORATION (JP) 1998-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110006295-A1 COMPOUNDS HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES NR2E3, NR4A2, NR4A3 PTGER4 561/4885CYP19A1 3603/4885P2RX4 1136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.