Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689666 | 0.92 | CYP19A1 (0.64) | PTGER4CYP19A1LMNAPSMD14P2RX4 | |
| SCHEMBL30676985 | 0.87 | PTGER4 (0.55) | PTGER4CYP19A1LMNAPSMD14P2RX4 | |
| SCHEMBL689732 | 0.87 | PTGER4 (0.55) | PTGER4CYP19A1LMNAPSMD14P2RX4 | |
| SCHEMBL28392221 | 0.86 | P2RX4 (0.61) | PTGER4CYP19A1LMNAPSMD14P2RX4 | |
| SCHEMBL4780793 | 0.86 | PTGER4 (0.55) | PTGER4CYP19A1LMNAPSMD14P2RX4 | |
| SCHEMBL4779161 | 0.84 | PTGER4 (0.48) | PTGER4CYP19A1LMNAPSMD14HDAC6 | |
| SCHEMBL8173273 | 0.84 | IP6K1 (0.47) | CYP19A1LMNAPSMD14P2RX4HDAC6 | |
| SCHEMBL8173275 | 0.84 | IP6K1 (0.47) | CYP19A1LMNAPSMD14P2RX4HDAC6 | |
| SCHEMBL4793959 | 0.83 | PTGER4 (0.55) | PTGER4CYP19A1LMNAPSMD14P2RX4 | |
| SCHEMBL8154947 | 0.82 | CYP19A1 (0.77) | CYP19A1P2RX4HDAC6DNM1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080770-A | SUBSTITUTED 1,2,3-TRIAZOLE OR 1,2,4-TRIAZOLE COMPOUND | NOVO NORDISK A/S (DK) | 2000-06-27 | — | — | US | disclosed |
| US-6063800-A | Modulators of molecules with phosphotyrosine recognition units | NOVO NORDISK A/S (DK) | 2000-05-16 | — | — | US | disclosed |
| US-5972978-A | FOR USE IN TREATMENT OF HUMAN AND ANIMAL DISORDERS, USE FOR PURIFICATION OF PROTEINS OR GLYCOPROTEINS, USE IN DIAGNOSIS | NOVO NORDISK A/S (DK) | 1999-10-26 | — | — | US | disclosed |
| US-5958957-A | PROTEIN TYROSINE PHOSPHATASES, PROTEINS WITH SRC-MONOLOGY 2-DOMAINS; ANTICARCINOGENIC,-TUMOR AND DIABETIC AGENTS; PURIFICATION OF PROTEINS AND GLYCOPROTEINS; MEDICAL DIAGNOSIS | NOVO NORDISK A/S (DK) | 1999-09-28 | — | — | US | disclosed |
| WO-1997040017-A2 | MODULATORS OF MOLECULES WITH PHOSPHOTYROSINE RECOGNITION UNITS | NOVO NORDISK A/S (DK) | 1997-10-30 | — | — | WO | disclosed |