Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 6/20 | 0.73 |
| ▸ | ACE | P12821 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | CTSS | P25774 | 3/20 | 0.63 |
| ▸ | CTSK | P43235 | 2/20 | 0.63 |
| ▸ | CTSL | P07711 | 1/20 | 0.63 |
| ▸ | CTSB | P07858 | 1/20 | 0.63 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.57 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.56 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.56 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.56 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.56 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.56 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.56 |
| ▸ | MME | P08473 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9101393 | 1.00 | REN (0.73) | RENACEMAPK1CTSSCTSK | |
| SCHEMBL5994686 | 1.00 | REN (0.73) | RENACEMAPK1CTSSCTSK | |
| SCHEMBL3046634 | 1.00 | REN (0.73) | RENACEMAPK1CTSSCTSK | |
| SCHEMBL9101385 | 1.00 | REN (0.73) | RENACEMAPK1CTSSCTSK | |
| SCHEMBL3824374 | 0.99 | REN (0.71) | RENACEMAPK1CTSSCTSK | |
| SCHEMBL21244275 | 0.99 | REN (0.71) | RENACEMAPK1CTSSCTSK | |
| SCHEMBL3499528 | 0.99 | REN (0.71) | RENACEMAPK1CTSSCTSK | |
| SCHEMBL17629479 | 0.99 | REN (0.71) | RENACEMAPK1CTSSCTSK | |
| SCHEMBL19341935 | 0.99 | REN (0.71) | RENACEMAPK1CTSSCTSK | |
| SCHEMBL9551232 | 0.98 | REN (0.73) | RENACEMAPK1CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699079-B1 | BIOACTIVE AND/OR TARGETED DENDRIMER CONJUGATES COMPRISING GENETIC MATERIALS | DOW CHEMICAL CO (US) | 2004-09-29 | — | — | EP | disclosed |
| US-6312679-B1 | Dense star polymer conjugates as dyes | THE DOW CHEMICAL COMPANY | 2001-11-06 | — | — | US | disclosed |
| US-6177414-B1 | POLYMAMINOAMIDE DENDRIMER STAR POLYMER CARRYING SALICYLIC ACID MOIETIES; DRUG DELIVERY | THE DOW CHEMICAL COMPANY | 2001-01-23 | — | — | US | disclosed |
| US-5714166-A | Bioactive and/or targeted dendrimer conjugates | THE DOW CHEMICAL COMPANY (US) | 1998-02-03 | — | — | US | disclosed |
| US-5527524-A | AGRICULTURAL, PHARMACEUTICAL, DRUG DELIVERY | THE DOW CHEMICAL COMPANY (US) | 1996-06-18 | — | — | US | disclosed |
| EP-0705324-A1 | GRANULAR DETERGENT COMPOSITION COMPRISING A SURFACTANT AND ANTIFOAMING COMPONENT | THE PROCTER & GAMBLE COMPANY (US) | 1996-04-10 | — | — | EP | disclosed |
| EP-0699079-A1 | BIOACTIVE AND/OR TARGETED DENDRIMER CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1996-03-06 | — | — | EP | disclosed |
| EP-0705324-A4 | GRANULAR DETERGENT COMPOSITION COMPRISING A SURFACTANT AND ANTIFOAMING COMPONENT | PROCTER & GAMBLE (US) | 1996-02-13 | — | — | EP | disclosed |
| WO-1995024221-A1 | BIOACTIVE AND/OR TARGETED DENDRIMER CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1995-09-14 | — | — | WO | disclosed |
| WO-1995002665-A1 | GRANULAR DETERGENT COMPOSITION COMPRISING A SURFACTANT AND ANTIFOAMING COMPONENT | THE PROCTER & GAMBLE COMPANY (US) | 1995-01-26 | — | — | WO | disclosed |
| US-5338532-A | Star polymer as carrier for drugs, agricultural compounds | THE DOW CHEMICAL COMPANY (US) | 1994-08-16 | — | — | US | disclosed |