Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 18/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899861 | 0.84 | CTSS (0.48) | CTSSCTSK | |
| SCHEMBL6899349 | 0.82 | CTSS (0.48) | CTSSCTSK | |
| SCHEMBL6900516 | 0.81 | CTSS (0.56) | CTSSCTSK | |
| SCHEMBL6900464 | 0.78 | CTSS (0.57) | CTSSCTSK | |
| SCHEMBL2146720 | 0.78 | CTSS (0.77) | CTSSCTSK | |
| SCHEMBL6900980 | 0.76 | CTSS (0.67) | CTSSCTSK | |
| SCHEMBL2146640 | 0.76 | CTSS (0.47) | CTSSCTSK | |
| SCHEMBL6899247 | 0.75 | CTSS (0.65) | CTSSCTSK | |
| Trifluoroacetic Acid SCHEMBL2146372 | 0.74 | CTSS (0.70) | CTSSCTSK | |
| SCHEMBL6897888 | 0.73 | CTSS (0.57) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011086125-A1 | 1H-[1,2,3]TRIAZOLO[4,5-c]PYRIDINE-4-CARBONITRILE DERIVATIVES | N.V. ORGANON (NL) | 2011-07-21 | — | — | WO | disclosed |