⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11374431 | 0.92 | — | — | |
| SCHEMBL4250570 | 0.90 | POLB (0.39) | — | |
| SCHEMBL462118 | 0.83 | — | — | |
| SCHEMBL826294 | 0.83 | POLB (0.48) | — | |
| SCHEMBL827143 | 0.83 | POLB (0.48) | — | |
| SCHEMBL197964 | 0.80 | POLB (0.46) | — | |
| SCHEMBL469931 | 0.80 | POLB (0.46) | — | |
| SCHEMBL472069 | 0.80 | POLB (0.46) | — | |
| SCHEMBL20565098 | 0.80 | POLB (0.46) | — | |
| SCHEMBL827865 | 0.80 | POLB (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1264865-B1 | Addition-curable silicone composition with improved adhesion and cured silicone product | DOW CORNING (US) | 2004-05-12 | — | — | EP | disclosed |
| US-6512037-B1 | Hydrosilylation addition-curable silicone composition containing a titanium or zirconium compound having at least one aliphatic carbon-carbon multiple bond | DOW CORNING CORPORATION | 2003-01-28 | — | — | US | disclosed |
| US-20030013802-A1 | SILICONE COMPOSITION AND CURED SILICONE PRODUCT | DOW CORNING CORPORATION | 2003-01-16 | — | — | US | disclosed |
| EP-1264865-A1 | Addition-curable silicone composition with improved adhesion and cured silicone product | Dow Corning Corporation (US) | 2002-12-11 | — | — | EP | disclosed |
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |