SCHEMBL6897809

SCHEMBL6897809

Nc1[c]ccc(-c2ccc3ccccc3c2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
CYP1A2 P05177 1/20 0.46
ALOX5 P09917 1/20 0.46
SRC P12931 1/20 0.45
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
HSD17B1 P14061 1/20 0.44
HSD17B2 P37059 1/20 0.44
ALDH1A1 P00352 4/20 0.43
CYP3A4 P08684 2/20 0.43
HSD17B10 Q99714 2/20 0.43
KDM4E B2RXH2 3/20 0.43
NPC1 O15118 2/20 0.43
MAPT P10636 2/20 0.43
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
AR P10275 1/20 0.43
NFKB1 P19838 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3296186 0.79 MAOA (0.48) ALOX5ALDH1A1CYP3A4HSD17B10KDM4E
SCHEMBL2448879 0.78 ESR1 (0.48) ESR1ESR2CYP1A2ALOX5SRC
SCHEMBL9536490 0.77 ESR1 (0.57) ESR1ESR2CYP1A2ALOX5CA1
SCHEMBL2257746 0.77 ESR1 (0.47) ESR1ESR2CYP1A2ALOX5SRC
SCHEMBL5013872 0.76 ESR1 (0.71) ESR1ESR2CYP1A2ALOX5CA1
SCHEMBL30239998 0.76 ESR1 (0.71) ESR1ESR2CYP1A2ALOX5CA1
SCHEMBL30239993 0.76 ESR1 (0.71) ESR1ESR2CYP1A2ALOX5CA1
SCHEMBL239121 0.76 ESR1 (0.71) ESR1ESR2CYP1A2ALOX5CA1
SCHEMBL15902840 0.76 ESR1 (0.71) ESR1ESR2CYP1A2ALOX5CA1
SCHEMBL30603836 0.76 ESR1 (0.71) ESR1ESR2CYP1A2ALOX5CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2004315495-A NEW ARYLAMINE DERIVATIVE HAVING FLUORENE SKELETON, SYNTHETIC INTERMEDIATE OF THE SAME, METHOD FOR PRODUCING THEM AND ORGANIC EL ELEMENT TOSOH CORP 2004-11-11 JP disclosed