Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | PYGM | P11217 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6900340 | 0.90 | MCHR1 (0.68) | MCHR1MEN1KMT2ACACNA1HCACNA1B | |
| SCHEMBL7051105 | 0.86 | MEN1 (0.58) | MCHR1MEN1KMT2ATSHRCACNA1H | |
| SCHEMBL6926029 | 0.86 | MCHR1 (0.55) | MCHR1MEN1KMT2ATSHRNPC1 | |
| SCHEMBL6897990 | 0.85 | MCHR1 (0.53) | MCHR1MEN1KMT2ATSHRCACNA1H | |
| SCHEMBL6922307 | 0.85 | MCHR1 (0.54) | MCHR1MEN1KMT2ATSHRNPC1 | |
| SCHEMBL6811436 | 0.84 | MCHR1 (0.75) | MCHR1MEN1KMT2ACASP3SENP8 | |
| SCHEMBL6892159 | 0.83 | MCHR1 (0.93) | MCHR1MEN1KMT2ACASP3SENP8 | |
| SCHEMBL6926500 | 0.81 | MCHR1 (0.69) | MCHR1CACNA1HCACNA1BHTR2C | |
| SCHEMBL6927041 | 0.80 | MCHR1 (0.55) | MCHR1MEN1KMT2ACACNA1HCACNA1B | |
| SCHEMBL6898482 | 0.80 | MCHR1 (0.68) | MCHR1CACNA1HCACNA1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100485-A4 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2004-06-09 | — | — | EP | disclosed |
| EP-1100485-A1 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006146-A9 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2000-08-03 | — | — | WO | disclosed |
| WO-2000006146-A1 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |