Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 14/20 | 0.68 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6926500 | 0.89 | MCHR1 (0.69) | MCHR1HTR2CGAACACNA1HCACNA1B | |
| SCHEMBL6927041 | 0.87 | MCHR1 (0.55) | MCHR1HTR2CGAACACNA1HCACNA1B | |
| SCHEMBL6927883 | 0.87 | MCHR1 (0.58) | MCHR1HTR2CGAAALDH1A1 | |
| SCHEMBL6900340 | 0.87 | MCHR1 (0.68) | MCHR1HTR2CGAACACNA1HCACNA1B | |
| SCHEMBL6921912 | 0.86 | MCHR1 (0.54) | MCHR1HTR2CGAACACNA1HCACNA1B | |
| SCHEMBL6927049 | 0.86 | GAA (0.57) | MCHR1HTR2CGAACACNA1HCACNA1B | |
| SCHEMBL6926051 | 0.85 | MCHR1 (0.53) | MCHR1HTR2CGAACACNA1HCACNA1B | |
| SCHEMBL6898504 | 0.85 | GAA (0.56) | MCHR1LTA4HGAACACNA1HCACNA1B | |
| SCHEMBL6898486 | 0.84 | GAA (0.58) | MCHR1LTA4HGAACACNA1HCACNA1B | |
| SCHEMBL6801515 | 0.82 | MCHR1 (0.80) | MCHR1LTA4HHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100485-A4 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2004-06-09 | — | — | EP | disclosed |
| EP-1100485-A1 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006146-A9 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2000-08-03 | — | — | WO | disclosed |
| WO-2000006146-A1 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |